Evidence map›Paper›PMID 31014366›Full record

ArticleCritical care (London, England)2019

Control of respiratory drive by extracorporeal CO

Christian Karagiannidis, Stephan Strassmann, Sarah Schwarz, Michaela Merten, Eddy Fan, Jennifer Beck, Christer Sinderby, Wolfram Windisch

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

  1. Extracorporeal COCritical care (London, England) · 2026
    Trial
  2. Article
  3. ECMO-weaning facilitated by neurally adjusted ventilatory assist (NAVA): a case for principal clarification.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Article
  4. Is there still a place for ECCOMedizinische Klinik, Intensivmedizin und Notfallmedizin · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Physiological effects of adding ECCOAnnals of intensive care · 2020
    Article
  11. Correlation of Arterial COJournal of clinical medicine · 2020
    Article
  12. Article
  13. Article
  14. Review
  15. Low-flow assessment of current ECMO/ECCOCritical care (London, England) · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Christian KaragiannidisDepartment of Pneumology and Critical Care Medicine, Cologne-Merheim Hospital, ARDS and ECMO Centre, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, Ostmerheimer Strasse 200, D-51109, Cologne, Germany. Christian.Karagiannidis@uni-wh.de.ORCID http://orcid.org/0000-0003-3247-2849
Stephan StrassmannDepartment of Pneumology and Critical Care Medicine, Cologne-Merheim Hospital, ARDS and ECMO Centre, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, Ostmerheimer Strasse 200, D-51109, Cologne, Germany.
Sarah SchwarzDepartment of Pneumology and Critical Care Medicine, Cologne-Merheim Hospital, ARDS and ECMO Centre, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, Ostmerheimer Strasse 200, D-51109, Cologne, Germany.
Michaela MertenDepartment of Pneumology and Critical Care Medicine, Cologne-Merheim Hospital, ARDS and ECMO Centre, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, Ostmerheimer Strasse 200, D-51109, Cologne, Germany.
Eddy FanInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.
Jennifer BeckKeenan Research Centre for Biomedical Science and Department of Critical Care Medicine, St. Michael's Hospital, Toronto, Canada.
Christer SinderbyKeenan Research Centre for Biomedical Science and Department of Critical Care Medicine, St. Michael's Hospital, Toronto, Canada.
Wolfram WindischDepartment of Pneumology and Critical Care Medicine, Cologne-Merheim Hospital, ARDS and ECMO Centre, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, Ostmerheimer Strasse 200, D-51109, Cologne, Germany.
Witten/Herdecke University · DESt. Michael's Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVeno-venous extracorporeal CO

methodsA physiological study of the electrical activity of the diaphragm (Edi) response was conducted with varying degrees of extracorporeal CO

resultsTwenty COPD patients (SAPS II 37 ± 5.6, age 57 ± 9 years) treated with vv-ECCO

conclusionsThis study demonstrates for the first time the usefulness of the Edi signal to monitor and guide patients with severe acute exacerbation of COPD on vv-ECCO

Indexed as

AgedAnalysis of VarianceBlood Gas AnalysisCarbon DioxideFemaleHemofiltrationHumansInteractive Ventilatory SupportMaleMiddle AgedNoninvasive VentilationPulmonary Disease, Chronic ObstructiveSimplified Acute Physiology ScoreCarbon DioxideCOPDExacerbationExtracorporeal carbon dioxide removalNeurally adjusted ventilatory assistNon-invasive ventilation

Identifiers

PMID31014366
PMCPMC6480839
OpenAlexW2947401158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.