Evidence map›Paper›PMID 31014287›Full record

ArticleBMC cancer2019

Factors associated with low adherence to cervical cancer follow-up retest among HPV+/ cytology negative women: a study in programmatic context in a low-income population in Argentina.

Juan Gago, Melisa Paolino, Silvina Arrossi

Abstract read
In one paragraph

Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Implementation of second round of HPV-based screening for cervical cancer in programmatic contexts in Argentina.Revista panamericana de salud publica = Pan American journal of public health · 2025
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  11. Adherence to Dysphagia Treatment Recommendations: A Conceptual Model.Journal of speech, language, and hearing research : JSLHR · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan GagoPrograma Nacional de Prevención de Cancer Cervicouterino/Instituto Nacional del Cáncer (Argentina), Julio A. Roca 781, Piso 7, Buenos Aires, Argentina.
Melisa PaolinoCentro de Estudios de Estado y Sociedad/Consejo Nacional de Investigaciones Científicas y Técnicas, Sánchez de Bustamante 27, Buenos Aires, Argentina.
Silvina ArrossiCentro de Estudios de Estado y Sociedad/Consejo Nacional de Investigaciones Científicas y Técnicas, Sánchez de Bustamante 27, Buenos Aires, Argentina. silviarrossi2020@gmail.com.

Funding

DEVELOPING SUSTAINABLE INFLUENZA SURVEILLANCE NETWORKS AND RESPONSE TO AVIAN AND U51IP000337 · IP · NATIONAL INSTITUTE OF HEALTH · PI KAZI, BIRJEES MAZHER · 2009 to 2013
$2.4M
FIC/SCHOLARS-IN-RESIDENCEF15TW000337 · FIC · U.S. NATIONAL INSTITUTES OF HEALTH · PI ANDRADE, ZILTON A · 1990 to 1993
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NCIRD CDC HHS U51 IP000337
6 · The paper itself

Abstract

backgroundCervical Cancer is still a major public health challenge in low and middle-income countries. HPV testing has been an innovative approach, which was introduced in Argentina for women aged 30+ through the Jujuy Demonstration Project (JDP) carried out between 2012 and 2014. After a positive HPV-test, cytology is used as triage method. Under this protocol, the group of women with HPV+ and normal cytology are recommended to repeat the test within 12-18 months. Studies have shown that this group has increased risk of CIN2+, however, assuring high levels of repeating test among these women is difficult to achieve. We analyze those factors associated with lower re-test attendance among HPV+/ cytology negative women at a programmatic level in low-middle income settings.

methodsWe used data of women aged 30+ HPV-tested in the JDP and followed until 2018 (n = 49,565). We performed a set of different adjusted logistic regression models. Primary outcomes were re-test attendance and re-test attendance within recommended timeframe. We assessed as covariates age, health insurance status, year of HPV-testing, Pap testing in the past 3 years, HPV-testing modality (clinician-collected (CC) tests/self-collected (SC) tests), and span between HPV-test collection and report of results.

resultsForty nine thousand five hundred sixty five women were HPV-tested and 6742 had a positive HPV-test. Among HPV+ women, a total of 4522 were HPV+/Cytology negative (67.1%). In total, 3172 HPV+/Cytology negative women (70.1%) had a record of a second HPV test as of March 2018. Only 1196 women (26%) completed the second test within the timeframe. Women with no record of a previous Pap (OR: 0.46, 95% CI: 0.4-0.53, p < 0.001), aged 64+ (OR: 0.46, 95% CI: 0.31-0.68, p < 0.001) were less likely to be retested; while women with clinician-collected samples had higher odds of being re-tested (OR: 1.42, 95% CI: 1.06-1.91, p < 0.001).

conclusionsLow re-test rates were found in HPV +/ normal cytology women. Tailored interventions are needed to increase the effectiveness of the screening in this group, especially for those women with characteristics associated to lower attendance.

Indexed as

AdultAgedArgentinaCytodiagnosisEarly Detection of CancerFemaleFollow-Up StudiesHumansMiddle AgedPapillomaviridaePapillomavirus InfectionsPatient CompliancePovertyPrognosisUterine Cervical DysplasiaUterine Cervical NeoplasmsAdherenceCervical CancerFollow-upHPVHPV test

Identifiers

PMID31014287
PMCPMC6480915

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.