ArticleBrain sciences2019
Hypothesis: Astrocyte Foot Processes Detachment from the Neurovascular Unit in Female Diabetic Mice May Impair Modulation of Information Processing-Six Degrees of Separation.
Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Clinical neurovascular coupling through cerebrovascular reserve and cognitive function.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- A Closer Look at the Perivascular Unit in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus.Biomedicines · 2024Review
- Bridging metabolic syndrome and cognitive dysfunction: role of astrocytes.Frontiers in endocrinology · 2024Review
- Low-intensity open-field blast exposure effects on neurovascular unit ultrastructure in mice.Acta neuropathologica communications · 2023Article
- Article
- Neurovascular Coupling in Type 2 Diabetes With Cognitive Decline. A Narrative Review of Neuroimaging Findings and Their Pathophysiological Implications.Frontiers in endocrinology · 2022Review
- Three-dimensional remodeling of functional cerebrovascular architecture and gliovascular unit in leptin receptor-deficient mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Deficient Leptin Cellular Signaling Plays a Key Role in Brain Ultrastructural Remodeling in Obesity and Type 2 Diabetes Mellitus.International journal of molecular sciences · 2021Review
- Type 2 Diabetes Mellitus Increases The Risk of Late-Onset Alzheimer's Disease: Ultrastructural Remodeling of the Neurovascular Unit and Diabetic Gliopathy.Brain sciences · 2019Review
Corrections and comments
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Authors and funding
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Abstract
Astrocytes via their foot processes (ACfp) are specialized connecting cells, and they structurally connect the neurovascular unit (NVU) mural cells to neurons. Astrocytes provide homeostatic mechanisms for structural connections and provide communication between the NVU and regional neurons for functional hyperemia in regions of increased neuronal activity (neurovascular coupling). Previously, our group has demonstrated a detachment, separation, and retraction of ACfp in diabetic
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