Evidence map›Paper›PMID 31013932›Full record

ArticleMarine drugs2019

Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosis through Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes.

Cheol Park, Hee-Jae Cha, Su Hyun Hong, Gi-Young Kim, Suhkmann Kim, Heui-Soo Kim, Byung Woo Kim, You-Jin Jeon, Yung Hyun Choi

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Anti-Melanogenic Activities ofFoods (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Phloroglucinol Enhances Anagen Signaling and Alleviates HJournal of microbiology and biotechnology · 2024
    Article
  10. The Ocean's Pharmacy: Health Discoveries in Marine Algae.Molecules (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Fucoidan Isolated fromMarine drugs · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Cheol ParkDepartment of Molecular Biology, College of Natural Sciences, Dong-eui University, Busan 47340, Korea. parkch@deu.ac.kr.
Hee-Jae ChaDepartment of Parasitology and Genetics, College of Medicine, Kosin University, Busan 49267, Korea. hcha@kosin.ac.kr.ORCID 0000-0002-6963-2685
Su Hyun HongDepartment of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Korea. hongsh@deu.ac.kr.
Gi-Young KimDepartment of Marine Life Sciences, School of Marine Biomedical Sciences, Jeju National University, Jeju 63243, Korea. immunkim@jejunu.ac.kr.
Suhkmann KimDepartment of Chemistry, College of Natural Sciences, Pusan National University, Busan 46241, Korea. suhkmann@gmail.com.
Heui-Soo KimDepartment of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 46241, Korea. khs307@pusan.ac.kr.
Byung Woo KimBiopharmaceutical Engineering Major, Division of Applied Bioengineering, College of Engineering, Dong-eui University, Busan 47340, Korea. bwkim@deu.ac.kr.
You-Jin JeonDepartment of Marine Life Sciences, School of Marine Biomedical Sciences, Jeju National University, Jeju 63243, Korea. youjinj@jejunu.ac.kr.ORCID 0000-0003-3299-7266
Yung Hyun ChoiDepartment of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Korea. choiyh@deu.ac.kr.ORCID 0000-0002-1454-3124
Dong-Eui University · KRJeju National University · KRPusan National University · KRKosin University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phloroglucinol (PG) is a component of phlorotannins, which are abundant in marine brown alga species. Recent studies have shown that PG is beneficial in protecting cells from oxidative stress. In this study, we evaluated the protective efficacy of PG in HaCaT human skin keratinocytes stimulated with oxidative stress (hydrogen peroxide, H

Indexed as

Adenosine TriphosphateAntioxidantsApoptosisCaspase 3Cell LineCytochromes cDNA DamageHeme Oxygenase-1HumansHydrogen PeroxideKeratinocytesNF-E2-Related Factor 2Oxidative StressPhloroglucinolProtective AgentsProto-Oncogene Proteins c-bcl-2Adenosine TriphosphateAntioxidantsCaspase 3Cytochromes cHeme Oxygenase-1HMOX1 protein, humanHydrogen PeroxideNFE2L2 protein, humanNF-E2-Related Factor 2PhloroglucinolProtective AgentsProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpecieskeratinocytesNrf2/HO-1oxidative stressphloroglucinolROS

Identifiers

PMID31013932
PMCPMC6520966
OpenAlexW2938875627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.