Evidence map›Paper›PMID 31013910›Full record

ArticleJournal of clinical medicine2019

Repetitive Transcranial Magnetic Stimulation Therapy (rTMS) for Endometriosis Patients with Refractory Pelvic Chronic Pain: A Pilot Study.

Anne Pinot-Monange, Xavier Moisset, Pauline Chauvet, Anne-Sophie Gremeau, Aurélie Comptour, Michel Canis, Bruno Pereira, Nicolas Bourdel

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06333353 (Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06333353 narecruitingnot on this mapstarted 2024, after this paper: background citation

Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of OttawaRan2024 to 2027Enrolled152ConditionsEndometriosis, PainArmsReal RepetitiveTranscranial Magnetic Stimulation 5 sessions, Sham RepetitiveTranscranial Magnetic Stimulation 5 sessions, Real RepetitiveTranscranial Magnetic Stimulation 10 sessions, Sham RepetitiveTranscranial Magnetic Stimulation 10 sessions
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anne Pinot-MonangeDepartment of Gynecological Surgery, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. annepinot63@gmail.com.
Xavier MoissetDepartment of Neurology, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. xmoisset@chu-clermontferrand.fr.
Pauline ChauvetDepartment of Gynecological Surgery, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. pchauvet@chu-clermontferrand.fr.
Anne-Sophie GremeauDepartment of Gynecological Surgery, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. asgremeau@chu-clermontferrand.fr.
Aurélie ComptourDepartment of Gynecological Surgery, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. acomptour@chu-clermontferrand.fr.
Michel CanisDepartment of Gynecological Surgery, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. mcanis@chu-clermontferrand.fr.
Bruno PereiraBiostatistics Division (DRCI), CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. bpereira@chu-clermontferrand.fr.ORCID 0000-0003-3778-7161
Nicolas BourdelDepartment of Gynecological Surgery, CHU Clermont-Ferrand, 63000 Clermont-Ferrand, France. nbourdel@chu-clermontferrand.fr.ORCID 0000-0002-5527-4370
Centre Hospitalier Universitaire de Clermont-Ferrand · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis concerns more than 10% of women of reproductive age, frequently leading to chronic pelvic pain. Repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex (M1) induces an analgesic effect. This effect on chronic pelvic pain is yet to be evaluated. The objective of this study was to assess the feasibility and effect of rTMS to reduce pain and improve quality of life (QoL) in patients with chronic pelvic pain due to endometriosis. This pilot, open-labelled prospective trial examined treatment by neuronavigated rTMS over M1, one session per day for 5 consecutive days. Each session consisted of 1.500 pulses at 10 Hz. We assessed tolerance, pain change and QoL until 4 weeks post treatment with a primary endpoint at day 8. Twelve women were included. No patients experienced serious adverse effects or a significant increase in pain. Nine women reported improvement on the Patient Global Impression of Change with a reduction in both pain intensity and pain interference (5.1 ± 1.4 vs. 4.1 ± 1.6,

Indexed as

endometriosispaintranscranial magnetic stimulation

Identifiers

PMID31013910
PMCPMC6518231
OpenAlexW2937598987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.