Evidence map›Paper›PMID 31013842›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo.

Hsin-Yuan Chen, Po-Han Lin, Yin-Hwa Shih, Kei-Lee Wang, Yong-Han Hong, Tzong-Ming Shieh, Tsui-Chin Huang, Shih-Min Hsia

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  9. Review
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  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Uterine Fibroids and Diet.International journal of environmental research and public health · 2021
    Review
  18. Research Progress of PCNA in Reproductive System Diseases.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  19. The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis.Current opinion in endocrinology, diabetes, and obesity · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Hsin-Yuan ChenSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan. hsin246@gmail.com.
Po-Han LinSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan. phlin@tmu.edu.tw.
Yin-Hwa ShihDepartment of Healthcare Administration, Asia University, Taichung 41354, Taiwan. evashih@asia.edu.tw.
Kei-Lee WangDepartment of Nursing, Ching Kuo Institute of Managemnet and Health, Keelung 20301, Taiwan. kellywang@tmu.edu.tw.
Yong-Han HongDepartment of Nutrition, I-Shou University, Kaohsiung 84001, Taiwan. yonghan@isu.edu.tw.
Tzong-Ming ShiehDepartment of Dental Hygiene, College of Health Care, China Medical University, Taichung 40402, Taiwan. tmshieh@mail.cmu.edu.tw.
Tsui-Chin HuangPhD Program for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan. tsuichin@tmu.edu.tw.
Shih-Min HsiaSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan. bryanhsia@tmu.edu.tw.
Taipei Medical University · TWAsia University · TWChina Medical University · TWChing Kuo Institute of Management and Health · TWI-Shou University · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol (RSV) is a polyphenolic phytoalexin found in peanuts, grapes, and other plants. Uterine fibroids (UF) are benign growths that are enriched in extracellular matrix (ECM) proteins. In this study, we aimed to investigate the effects of RSV on UF using in vivo and in vitro approaches. In mouse xenograft models, tumors were implanted through the subcutaneous injection of Eker rat-derived uterine leiomyoma cells transfected with luciferase (ELT-3-LUC) in five-week-old female nude (Foxn1

Indexed as

ELT-3-LUC xenograft modelextracellular matrixresveratroluterine fibroids

Identifiers

PMID31013842
PMCPMC6523898
OpenAlexW2939092027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.