Evidence map›Paper›PMID 31013794›Full record

ArticleInternational journal of environmental research and public health2019

Effects of Long Noncoding RNA H19 Polymorphisms on Urothelial Cell Carcinoma Development.

Po-Jen Yang, Ming-Ju Hsieh, Tung-Wei Hung, Shian-Shiang Wang, Shiuan-Chih Chen, Meng-Chih Lee, Shun-Fa Yang, Ying-Erh Chou

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The relationship between long noncoding RNAInternational journal of medical sciences · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. TheBioMed research international · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Po-Jen YangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. cshy1030@csh.org.tw.
Ming-Ju HsiehInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. 170780@cch.org.tw.ORCID 0000-0001-9726-3234
Tung-Wei HungInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. a6152000@ms34.hinet.net.
Shian-Shiang WangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. sswdoc@vghtc.gov.tw.
Shiuan-Chih ChenInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. sccy399@yahoo.com.tw.
Meng-Chih LeeInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. mcl@csmu.edu.tw.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. ysf@csmu.edu.tw.ORCID 0000-0002-0365-7927
Ying-Erh ChouInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. intointo814@gmail.com.
Chung Shan Medical University Hospital · TWChina Medical University · TWMinistry of Health and Welfare · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urothelial cell carcinoma (UCC) is one of the major malignancies of the genitourinary tract, and it is induced by carcinogenic epidemiological risk factors. H19 is one of the most crucial long noncoding RNAs (lncRNAs) and is involved in various types of bladder cancer. In this study, we examined H19 single-nucleotide polymorphisms (SNPs) to investigate UCC susceptibility and clinicopathological characteristics. Using real-time polymerase chain reaction, we analyzed five SNPs of H19 in 431 UCC patients and 431 controls without cancer. The results showed that patients with UCC carrying the H19 rs217727 CT + TT and rs2107425 CT + TT genetic variants had a high risk of developing muscle invasive tumors (pT2-T4) (

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAdultAgedCarcinoma, Transitional CellCase-Control StudiesFemaleHumansMaleMiddle AgedRNA, Long NoncodingUrinary Bladder NeoplasmsH19 long non-coding RNARNA, Long NoncodingH19lncRNApolymorphismurothelial cell carcinoma

Identifiers

PMID31013794
PMCPMC6518101
OpenAlexW2937868153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.