Evidence map›Paper›PMID 31013779›Full record

ReviewInternational journal of molecular sciences2019

BNP and NT-proBNP as Diagnostic Biomarkers for Cardiac Dysfunction in Both Clinical and Forensic Medicine.

Zhipeng Cao, Yuqing Jia, Baoli Zhu

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07498868 (Detecting the Undetected), which is not on this map. Cited by 211 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
211citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07498868 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Detecting the Undetected: an Observational Cohort Study Evaluating the Health Economics, Clinical Utility, and Patient and Staff Experiences of Innovative Peptide Testing to Screen for Heart Failure in Lymphoedema Clinics

TypeobservationalSponsorSwansea Bay University Health BoardRan2026 to 2028Enrolled618ConditionsLymphedema, Lower Limb, Lymphedema, Heart Failure, Heart Failure (for Example, Fluid Overload)
3 · Its place in the literature

Who cites it

211 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  5. NT-proBNP in Different Patient Groups of COPD: A Systematic Review and Meta-Analysis.International journal of chronic obstructive pulmonary disease · 2023
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151 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhipeng CaoDepartment of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang 110122, China. zpcao@cmu.edu.cn.ORCID 0000-0002-4275-0788
Yuqing JiaDepartment of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang 110122, China. jia214@hotmail.com.
Baoli ZhuDepartment of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang 110122, China. zhu1127@hotmail.com.ORCID 0000-0001-6083-4187

Funding

National Natural Science Foundation of China 81273343Natural Science Foundation of Liaoning Province 20180530004
6 · The paper itself

Abstract

Currently, brain natriuretic peptide (BNP) and

Indexed as

BiomarkersForensic MedicineAnimalsDiagnosisGene Expression RegulationHeart FailureHeart Function TestsHumansNatriuretic Peptide, BrainPeptide FragmentsPrognosisProteolysisSeverity of Illness IndexSignal TransductionTranslational Research, BiomedicalBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)BNPcardiac dysfunctionforensic medicineheart failureNT-proBNPpostmortem biochemistry

Identifiers

PMID31013779
PMCPMC6515513

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.