Evidence map›Paper›PMID 31013753›Full record

ArticleBiosensors2019

Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform.

Sarah M Robinson, Zuliang Shen, Jon R Askim, Christopher B Montgomery, Herman O Sintim, Steve Semancik

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sarah M RobinsonDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. smenio@umd.edu.ORCID 0000-0001-5189-3900
Zuliang ShenDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. zuliangs@gmail.com.
Jon R AskimBiomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA. jon.r.askim@gmail.com.
Christopher B MontgomeryBiomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA. chip@nist.gov.
Herman O SintimDepartment of Chemistry, Institute for Drug Discovery, Purdue University, West Lafayette, IN 47907, USA. hsintim@purdue.edu.ORCID 0000-0002-2280-9359
Steve SemancikBiomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA. stephen.semancik@nist.gov.
National Institute of Standards and Technology · USPurdue University West Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of technologies for rapid screening of DNA secondary structure thermal stability and the effects on stability for binding of small molecule drugs is important to the drug discovery process. In this report, we describe the capabilities of an electrochemical, microdevice-based approach for determining the melting temperatures (

Indexed as

Biosensing TechniquesDiminazeneDNAElectrochemical TechniquesLigandsProflavineTransition TemperatureDiminazenediminazene aceturateDNALigandsProflavineDNAelectrochemical sensorligand-based stabilizationmelting profilesmicrofabricationmicroheaterrapid temperature controlsquare wave voltammetry

Identifiers

PMID31013753
PMCPMC6628196
OpenAlexW2939093378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.