Evidence map›Paper›PMID 31013719›Full record

ReviewNutrients2019

Protein Supplements and Their Relation with Nutrition, Microbiota Composition and Health: Is More Protein Always Better for Sportspeople?

Anna Kårlund, Carlos Gómez-Gallego, Anu M Turpeinen, Outi-Maaria Palo-Oja, Hani El-Nezami, Marjukka Kolehmainen

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 119 citations in OpenAlex.

  1. Trial
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  3. Review
  4. Article
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Foods (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Article
  14. Gut microbiome composition: link between sports performance and protein absorption?Journal of the International Society of Sports Nutrition · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Anna KårlundInstitute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. anna.karlund@uef.fi.
Carlos Gómez-GallegoInstitute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. carlos.gomezgallego@uef.fi.ORCID 0000-0003-0219-1827
Anu M TurpeinenValio Ltd, R&D, P.O. Box 30, 00039 Valio, Finland. anu.turpeinen@valio.fi.
Outi-Maaria Palo-OjaBusiness School, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. outi-maaria.palo-oja@uef.fi.ORCID 0000-0001-8671-7982
Hani El-NezamiInstitute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. hani.el-nezami@uef.fi.
Marjukka KolehmainenInstitute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. marjukka.kolehmainen@uef.fi.
University of Eastern Finland · FIValio (Finland) · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sports nutrition products are developed and targeted mainly for athletes to improve their nutrient intake, performance, and muscle growth. The fastest growing consumer groups for these products are recreational sportspeople and lifestyle users. Although athletes may have elevated physiological protein requirements and they may benefit from dietary supplements, the evidence regarding the role of dietary protein and supplements in the nutrition of recreational sportspeople and sedentary populations is somewhat complex and contradictory. In high-protein diets, more undigested protein-derived constituents end up in the large intestine compared to moderate or low-protein diets, and hence, more bacterial amino acid metabolism takes place in the colon, having both positive and negative systemic and metabolic effects on the host. The aim of the present review is to summarize the impact of the high-protein products and diets on nutrition and health, in sportspeople and in sedentary consumers. We are opening the debate about the current protein intake recommendations, with an emphasis on evidence-based effects on intestinal microbiota and personalized guidelines regarding protein and amino acid supplementation in sportspeople and lifestyle consumers.

Indexed as

Dietary SupplementsExerciseNutritional StatusSedentary BehaviorSportsAmino AcidsBacteriaDietary ProteinsDigestionGastrointestinal MicrobiomeHumansIntestine, LargeRecommended Dietary AllowancesSports Nutritional Physiological PhenomenaAmino AcidsDietary Proteinsamino aciddietary supplements marketgut microbiotahigh-protein dietsprotein fermentationprotein metabolismsports nutrition

Identifiers

PMID31013719
PMCPMC6521232
OpenAlexW2937251615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.