Evidence map›Paper›PMID 31013658›Full record

ArticleCancers2019

Prognostic Value of Genetic Alterations in Elderly Patients with Acute Myeloid Leukemia: A Single Institution Experience.

Maël Heiblig, Hélène Labussière-Wallet, Franck Emmanuel Nicolini, Mauricette Michallet, Sandrine Hayette, Pierre Sujobert, Adriana Plesa, Marie Balsat, Etienne Paubelle, Fiorenza Barraco and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Maël HeibligDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. mael.heiblig@live.fr.
Hélène Labussière-WalletDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. helene.labussiere-wallet@chu-lyon.fr.
Franck Emmanuel NicoliniDepartment of Hematology, Centre Léon Bérard, 69008 Lyon, France. franck-emmanuel.nicolini@lyon.unicancer.fr.
Mauricette MichalletDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. mauricette.michallet@lyon.unicancer.fr.
Sandrine HayetteLaboratory of Molecular Biology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. sandrine.hayette@chu-lyon.fr.
Pierre SujobertLaboratory of Molecular Biology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. pierre.sujobert@chu-lyon.fr.
Adriana PlesaLaboratory of Cytology and Immunology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. adriana.plesa@chu-lyon.fr.
Marie BalsatDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. marie.balsat@chu-lyon.fr.
Etienne PaubelleDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. etienne.paubelle@chu-lyon.fr.
Fiorenza BarracoDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. fiorenza.barraco@chu-lyon.fr.
Isabelle TigaudLaboratory of Cytogenetics, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. isabelle.tigaud@chu-lyon.fr.
Sophie DucastelleDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. sophie.ducastelle-lepretre@chu-lyon.fr.
Eric WattelDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. eric.wattel@chu-lyon.fr.
Gilles SallesDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. gilles.salles@chu-lyon.fr.
Xavier ThomasDepartment of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre Bénite, France. xavier.thomas@chu-lyon.fr.
Hospices Civils de Lyon · FRHôpital Lyon Sud · FRCentre Léon Bérard · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the outcome in younger adults with acute myeloid leukemia (AML) has improved, the benefit associated with standard intensive chemotherapy in older patients remains debatable. In this study, we investigated the incidence and the prognostic significance of genetic characteristics according to treatment intensity in patients aged 60 years or older. On the 495 patients of our cohort,

Indexed as

acute myeloid leukemiaelderlyminimal residual diseasemolecular markersprognosis

Identifiers

PMID31013658
PMCPMC6520979
OpenAlexW2939802369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.