Evidence map›Paper›PMID 31013656›Full record

ArticleMaterials (Basel, Switzerland)2019

Permeability versus Design in TPMS Scaffolds.

A P G Castro, T Pires, J E Santos, B P Gouveia, P R Fernandes

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  3. Review
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  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. [Design of new gradient scaffolds based on triply periodic minimal surfaces and study on its mechanical, permeability and tissue differentiation characteristics].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Porous Scaffold Design for Additive Manufacturing in Orthopedics: A Review.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A P G CastroIDMEC, Instituto Superior Técnico, Universidade de Lisboa, 1649-004 Lisboa, Portugal. andre.castro@tecnico.ulisboa.pt.
T PiresIDMEC, Instituto Superior Técnico, Universidade de Lisboa, 1649-004 Lisboa, Portugal. tiago.a.h.v.pires@tecnico.ulisboa.pt.
J E SantosIDMEC, Instituto Superior Técnico, Universidade de Lisboa, 1649-004 Lisboa, Portugal. jemidiocsantos@gmail.com.
B P GouveiaIDMEC, Instituto Superior Técnico, Universidade de Lisboa, 1649-004 Lisboa, Portugal. bgouveia@tecnico.ulisboa.pt.
P R FernandesIDMEC, Instituto Superior Técnico, Universidade de Lisboa, 1649-004 Lisboa, Portugal. paulo.rui.fernandes@tecnico.ulisboa.pt.

Funding

Fundacao para a Ciencia e Tecnologia LAETA project UID/EMS/50022/2019Fundacao para a Ciencia e Tecnologia PTDC/BBB-BMC/5655/2014
6 · The paper itself

Abstract

Scaffolds for bone tissue engineering are porous structures that serve as support for cellular growth and, therefore, new tissue formation. The present work assessed the influence of the porous architecture of triply periodic minimal surface (TPMS) scaffolds on their macroscopic permeability behavior, combining numerical and experimental methods. The TPMS scaffolds considered were Schwartz D, Schwartz P, and Gyroid, which have been previously studied for bone tissue engineering, with 70% porosity. On the experimental side, these scaffolds were produced by MultiJet 3D printing and tested for fluid passage to calculate their permeability through Darcy's Law. On the numerical side, finite element (FE) models of the scaffolds were simulated on ABAQUS® for fluid passage under compression to assess potential fluid concentration spots. The outcomes revealed that the design of the unit cell had a noticeable effect on both calculated permeability and FE computed fluid flow velocity, regardless of the identical porosity, with the Gyroid scaffold having higher permeability and the Schwartz P a lower probability of fluid trapping. Schwartz D had the worst outcomes in both testing modalities, so these scaffolds would most likely be the last choice for promoting cell differentiation onto bone cells. Gyroid and Schwartz P would be up for selection depending on the application and targeted bone tissue.

Indexed as

biomechanicsbone scaffoldsnumerical modelingpermeabilitytissue engineeringTPMS

Identifiers

PMID31013656
PMCPMC6515433

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.