Evidence map›Paper›PMID 31013568›Full record

ArticleInsects2019

The Effects of a Bacterial Endotoxin on Behavior and Sensory-CNS-Motor Circuits in

Oscar Istas, Abigail Greenhalgh, Robin Cooper

Open access · goldAbstract read
In one paragraph

Article in Insects, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prolonged Transcriptional Consequences in Survivors of Sepsis.International journal of molecular sciences · 2021
    Article
  8. Article
  9. Article
  10. Listening to your gut: immune challenge to the gut sensitizes body wall nociception in the caterpillarPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Oscar IstasDepartment of Biology, University of Kentucky, Lexington, KY 40506-0225, USA. owis222@g.uky.edu.
Abigail GreenhalghDepartment of Biology, University of Kentucky, Lexington, KY 40506-0225, USA. Abigail.Greenhalgh@uky.edu.ORCID 0000-0002-7559-1904
Robin CooperDepartment of Biology, University of Kentucky, Lexington, KY 40506-0225, USA. RLCOOP1@uky.edu.
University of Kentucky · US

Funding

Howard Hughes Medical Institute 52008116Univ of KY, Dept of Biology 000000
6 · The paper itself

Abstract

The effect of bacterial sepsis on animal behavior and physiology is complex due to direct and indirect actions. The most common form of bacterial sepsis in humans is from gram-negative bacterial strains. The endotoxin (lipopolysaccharide, LPS) and/or associated peptidoglycans from the bacteria are the key agents to induce an immune response, which then produces a cascade of immunological consequences. However, there are direct actions of LPS and associated peptidoglycans on cells which are commonly overlooked. This study showed behavioral and neural changes in larval

Indexed as

bacteriaDrosophilaintegrationlipopolysaccharidesmotorpeptidoglycanssensorysynapse

Identifiers

PMID31013568
PMCPMC6523965
OpenAlexW2937560073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.