Evidence map›Paper›PMID 31013486›Full record

ArticlePhysics in medicine and biology2019

A scalable database of organ doses for common diagnostic fluoroscopy examinations of children: procedures of current practice at the University of Florida.

Emily L Marshall, Dhanashree Rajderkar, Justin L Brown, Elliott J Stepusin, David Borrego, Wesley E Bolch

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emily L MarshallJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0001-7995-0671
Dhanashree RajderkarDepartment of Radiology, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0002-5962-2854
Justin L BrownMedical Physics Program, College of Medicine, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0002-3099-1998
Elliott J StepusinJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0002-3204-7730
David BorregoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America.ORCID 0000-0001-9868-5113
Wesley E BolchJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0002-7175-9968
University of Florida · USNational Institutes of Health · US

Funding

Risk of Pediatric and Adolescent Cancer Associated with Medical ImagingR01CA185687 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KWAN, MARILYN L, MIGLIORETTI, DIANA L · 2015 to 2019
$10.0M
In-Clinic Assessment of Organ Doses for Interventional Fluoroscopic ProceduresF31CA159464 · NCI · UNIVERSITY OF FLORIDA · PI BORREGO, DAVID · 2010 to 2015
$180k
NCI NIH HHS F31 CA159464NCI NIH HHS R01 CA185687
6 · The paper itself

Abstract

Of all the medical imaging modalities that utilize ionizing radiation, fluoroscopy proves to be the most difficult to assess values of patient organ dose owing to the dynamic and patient-specific nature of the irradiation geometry and its associated x-ray beam characteristics. With the introduction of the radiation dose structured report (RDSR) in the mid-2000s, however, computational tools have been developed to extract patient and procedure-specific data for each irradiation event of the study, and when coupled to a computational phantom of the patient, values of skin and internal organ dose may be assessed. Unfortunately, many legacy and even current diagnostic fluoroscopy units do not have RDSR reporting capabilities, thus limiting these dosimetry reporting advances. Nevertheless, knowledge of patient organ doses for patient care, as well as for radiation epidemiology studies, remains a research and regulatory priority. In this study, we created procedural outlines which document all radiation exposure information required for organ dose assessment, akin to a reference RDSR, for six common diagnostic fluoroscopy procedures performed at the University of Florida (UF) Shands Pediatric Hospital. These procedures include the voiding cystourethrogram, the gastrostomy-tube placement, the lower gastrointestinal study, the rehabilitation swallow, the upper gastrointestinal study, and the upper gastrointestinal study with follow through. These procedural outlines were used to develop an extensive database of organ doses for the 162-member UF/NCI (National Cancer Institute) library of pediatric hybrid phantoms, with each member varying combinations of sex, height, and weight. The organ dose assessment accounts for the varying x-ray fields, fluoroscopy time, relative concentration of x-ray contrast in the organs, and changes in the fluoroscope output due to patient size. Furthermore, we are also reporting organ doses normalized to total fluoroscopy time, reference point air kerma, and kerma-area product, effectively providing procedure dose coefficients. The extensive organ dose library produced in this study may be used prospectively for patient organ dose reporting or retrospectively in epidemiological studies of radiation-associated health risks.

Indexed as

Databases, FactualFluoroscopyRadiation DosageUniversitiesBody WeightChildChild, PreschoolFemaleHumansPhantoms, ImagingRadiation ExposureRadiometry

Identifiers

PMID31013486
PMCPMC13463352
OpenAlexW2941018016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.