Evidence map›Paper›PMID 31013338›Full record

ArticlePloS one2019

Pregnancy intention and contraceptive use among HIV-positive Malawian women at 4-26 weeks post-partum: A nested cross-sectional study.

Deus Thindwa, Megan Landes, Monique van Lettow, Annie Kanyemba, Ernest Nkhoma, Happy Phiri, Thokozani Kalua, Joep J van Oosterhout, Evelyn J Kim, Beth A Tippett Barr and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Deus ThindwaManagement Sciences for Health, Lilongwe, Malawi.ORCID 0000-0003-4845-7862
Megan LandesDignitas International, Zomba, Malawi.
Monique van LettowDignitas International, Zomba, Malawi.
Annie KanyembaManagement Sciences for Health, Lilongwe, Malawi.
Ernest NkhomaManagement Sciences for Health, Lilongwe, Malawi.
Happy PhiriManagement Sciences for Health, Lilongwe, Malawi.
Thokozani KaluaDepartment of HIV, Ministry of Health, Lilongwe, Malawi.
Joep J van OosterhoutDignitas International, Zomba, Malawi.ORCID 0000-0002-3441-0804
Evelyn J KimCenters for Disease Control and Prevention, Lilongwe, Malawi.
Beth A Tippett BarrCenters for Disease Control and Prevention, Lilongwe, Malawi.
NEMAPP Consortium
Public Health Institute of Malawi · MWUniversity of Toronto · CAMinistry of Health · MWUniversity of Malawi · MW

Funding

CGH CDC HHS U2G GH000721PEPFAR
6 · The paper itself

Abstract

backgroundAvoiding unintended pregnancies through family planning is a WHO strategy for preventing mother to child transmission of HIV (PMTCT) and maternal morbidity/mortality. We investigated factors associated with unintended index pregnancy, unmet contraceptive need, future pregnancy intention and current contraceptive use among Malawian women living with HIV in the Option B+ era.

methodsWomen who tested HIV positive at 4-26 weeks postpartum were enrolled into a cross-sectional study at high-volume Under-5 clinics. Structured baseline interviews included questions on socio-demographics, HIV knowledge, partner's HIV status/disclosure, ART use, pregnancy intention and contraceptive use. Logistic regression was used to determine factors associated with outcomes.

resultsWe enrolled 578 HIV-positive women between May 2015-May 2016; median maternal age was 28 years (y) (interquartile-range [IQR]: 23-32), median parity was 3 deliveries (IQR: 2-4) and median infant age was 7 weeks (IQR: 6-12). Overall, 41.8% women reported unintended index pregnancy, of whom 35.0% reported unmet contraceptive need and 65.0% contraceptive failure. In multivariable analysis, unintended index pregnancy was higher in ≥35y vs. 14-24y (adjusted Odds Ratio [aOR]: 2.1, 95% Confidence Interval [95%CI]: 1.0-4.2) and in women with parity ≥3 vs. primiparous (aOR: 2.9, 95%CI: 1.5-5.6). Unmet contraceptive need at conception was higher in 14-24y vs. ≥35y (aOR: 4.2, 95%CI: 1.8-9.9), primiparous vs. ≥3 (aOR: 8.3, 95%CI: 1.8-39.5), and women with a partner of unknown HIV-status (aOR: 2.2, 95%CI: 1.2-4.0). Current contraceptive use was associated with being on ART in previous pregnancy (aOR: 2.5, 95%CI: 1.5-3.9).

conclusionsHigh prevalence of unintended index pregnancy and unmet contraceptive need among HIV-positive women highlight the need for improved access to contraceptives. To help achieve reproductive goals and elimination of MTCT of HIV, integration of family planning into HIV care should be strengthened to ensure women have timely access to a wide range of family planning methods with low failure risk.

Indexed as

ContraceptionFamily Planning ServicesReproductive Techniques, AssistedAdultFemaleHIVHIV InfectionsHumansInfectious Disease Transmission, VerticalLogistic ModelsMalawiPostpartum PeriodPregnancyReligionYoung Adult

Identifiers

PMID31013338
PMCPMC6478345
OpenAlexW2940884881

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.