Evidence map›Paper›PMID 31012057›Full record

ArticleJournal of the American Society for Mass Spectrometry2019

Multiple Ion Transition Summation of Isotopologues for Improved Mass Spectrometric Detection of N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine.

Cameron S Movassaghi, Declan P McCarthy, Deepak Bhandari, Benjamin C Blount, Víctor R De Jesús

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Cameron S MovassaghiDivision of Laboratory Sciences (DLS), Tobacco and Volatiles Branch (TVB), Centers for Disease Control and Prevention (CDC), 4770 Buford Hwy NE, MS F-47, Atlanta, GA, 30341, USA.
Declan P McCarthyDivision of Laboratory Sciences (DLS), Tobacco and Volatiles Branch (TVB), Centers for Disease Control and Prevention (CDC), 4770 Buford Hwy NE, MS F-47, Atlanta, GA, 30341, USA.
Deepak BhandariDivision of Laboratory Sciences (DLS), Tobacco and Volatiles Branch (TVB), Centers for Disease Control and Prevention (CDC), 4770 Buford Hwy NE, MS F-47, Atlanta, GA, 30341, USA. dbhandari@cdc.gov.
Benjamin C BlountDivision of Laboratory Sciences (DLS), Tobacco and Volatiles Branch (TVB), Centers for Disease Control and Prevention (CDC), 4770 Buford Hwy NE, MS F-47, Atlanta, GA, 30341, USA.
Víctor R De JesúsDivision of Laboratory Sciences (DLS), Tobacco and Volatiles Branch (TVB), Centers for Disease Control and Prevention (CDC), 4770 Buford Hwy NE, MS F-47, Atlanta, GA, 30341, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Multiple ion transition summation of isotopologues (MITSI) is an adaptable and easy-to-implement methodology for improving analytical sensitivity, especially for halogenated compounds and otherwise abundant isotopologues. This novel application of signal summing was applied to measure and quantitate the two most abundant ion transitions of two isotopologues of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine (1DCV), a urinary metabolite of trichloroethylene (TCE). Because 1DCV is dichlorinated, only approximately half of the total potential signal is quantifiable when the monoisotopic ion transition (i.e., m/z 256 → 127 for

Indexed as

1DCVMass spectrometryN-Acetyl-S-(1,2-dichlorovinyl)-L-cysteineSignal summingTrichloroethylene

Identifiers

PMID31012057
PMCPMC7887456

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.