Evidence map›Paper›PMID 31012008›Full record

ArticleDoklady. Biochemistry and biophysics2019

A Novel PRE-Element from Drosophila virilis Genome as a Useful Model Silencer.

D A Chetverina, A V Mikhailova, P G Georgiev, M M Erokhin

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In one paragraph

Article in Doklady. Biochemistry and biophysics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D A ChetverinaInstitute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia.
A V MikhailovaInstitute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia.
P G GeorgievInstitute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia.
M M ErokhinInstitute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia. yermaxbio@yandex.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We tested the activity of the PRE element from the Drosophila virilis genome, which is the homologue of the known Drosophila melanogasterbxdPRE element from the regulatory region of the Ubx gene. It is easy to select unique primers to this element that do not occur in the Drosophila melanogaster genome. We showed that the studied PRE element causes a strong repression of the white marker gene upon insertion into the Drosophila melanogaster genome and interacts with the PcG proteins of the PRC1 and PhoRC complexes.

Indexed as

DNA Transposable ElementsGenome, InsectSilencer Elements, TranscriptionalAnimalsDrosophilaDrosophila ProteinsDNA Transposable ElementsDrosophila Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.