ArticleBrain topography2019
Neural Signatures of Social Inclusion in Borderline Personality Disorder Versus Non-suicidal Self-injury.
Article in Brain topography, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Social exclusion alters attention and autonomic regulation in adolescents with nonsuicidal self-injury.Translational psychiatry · 2026Article
- Frequency of bullying modulates amygdala response during social exclusion in participants with non-suicidal self-injury.European child & adolescent psychiatry · 2026Article
- The Experience of Goals and Rewards in Young People Who Self-Harm: A Qualitative Exploration.Healthcare (Basel, Switzerland) · 2025Article
- Reward-related neural activation during social media exposure in young women with non-suicidal self-injury: evidence for a continuum of severity in the reward network.Translational psychiatry · 2025Article
- The incremental validity of level of personality functioning over borderline personality features in associations with early adolescent social reward processing.Personality and mental health · 2025Article
- Social and Monetary Reward Processing in Youth with Early Emerging Personality Pathology: An RDoC-Informed Study.Research on child and adolescent psychopathology · 2024Article
- Altered gray matter volume and functional connectivity in adolescent borderline personality disorder with non-suicidal self-injury behavior.European child & adolescent psychiatry · 2024Article
- Neural correlates of social exclusion and overinclusion in patients with borderline personality disorder: an fMRI study.Borderline personality disorder and emotion dysregulation · 2023Article
- Rejection Distress Suppresses Medial Prefrontal Cortex in Borderline Personality Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Neurobiological correlates and attenuated positive social intention attribution during laughter perception associated with degree of autistic traits.Journal of neural transmission (Vienna, Austria : 1996) · 2023Article
- Borderline personality features and altered social feedback processing in emerging adults: An EEG study.Progress in neuro-psychopharmacology & biological psychiatry · 2023Article
- Neural Signatures of Error Processing in Depressed Adolescents with Comorbid Non-Suicidal Self-Injury (NSSI).Biomedicines · 2022Article
- Borderline Personality Disorder: Updates in a Postpandemic World.Focus (American Psychiatric Publishing) · 2022Review
- Aberrant Structural Connectivity of the Triple Network System in Borderline Personality Disorder Is Associated with Behavioral Dysregulation.Journal of clinical medicine · 2022Article
- Relationship between thyroid hormone and sex hormone levels and non-suicidal self-injury in male adolescents with depression.Frontiers in psychiatry · 2022Article
- Abnormal brain activity in nonsuicidal self-injury: a coordinate-based activation likelihood meta-analysis of functional neuroimaging studies.Psychoradiology · 2021Article
- Advancing a temporal framework for understanding the biology of nonsuicidal self- injury: An expert review.Neuroscience and biobehavioral reviews · 2021Review
- Brain responses to social feedback in internalizing disorders: A comprehensive review.Neuroscience and biobehavioral reviews · 2020Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Borderline personality disorder (BPD) is characterized by interpersonal disturbances and dysfunctional behavior such as non-suicidal self-injury (NSSI). We recently observed neural alterations in BPD during social inclusion by enhanced activations within the dorsomedial prefrontal cortex (dmPFC) and the posterior cingulate cortex (PCC). To examine the specificity of these neural alterations, we now investigated participants with NSSI but without BPD and compared them to BPD and healthy controls (HC). Considering the association between NSSI and BPD, we further examined neural commonalities during social inclusion. Fifteen females diagnosed with BPD, 16 with NSSI and 17 HC were investigated by fMRI and the cyberball paradigm, focusing on social inclusion (p < 0.05; FWE on cluster-level). To examine neural commonalities between BPD and NSSI compared to HC, we computed a conjunction analysis on neural activations under social inclusion. Significant increases in neural activation were observed in BPD within the dmPFC under social inclusion compared to NSSI and HC, whereas neural activations within the PCC did not differ between BPD and NSSI. The conjunction analysis revealed a common neurofunctional increase within the pregenual anterior cingulate cortex and the anterior insula in both, BPD and NSSI. We provide a further evidence regarding a disorder-specific neural reactivity within the dmPFC during social inclusion in BPD, whereas PCC activations may represent an unspecific neural alteration in BPD when compared to NSSI. In contrast, both clinical groups revealed a common neural increase within the salience network that may support the assumptions of a developmental continuum between these two psychiatric conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.