Evidence map›Paper›PMID 31011734›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2019

Optimized synthesis of luminescent silica nanoparticles by a direct micelle-assisted method.

Benedetta Del Secco, Luca Ravotto, Tatiana V Esipova, Sergei A Vinogradov, Damiano Genovese, Nelsi Zaccheroni, Enrico Rampazzo, Luca Prodi

Abstract read
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Nitroxides as Building Blocks for Nanoantioxidants.ACS applied materials & interfaces · 2021
    Article
  5. Article
  6. Phosphorescent MoSNanoscale advances · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benedetta Del SeccoDepartment of Chemistry "Giacomo Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy. enrico.rampazzo@unibo.it luca.prodi@unibo.it.ORCID http://orcid.org/0000-0001-8881-4575
Luca RavottoDepartments of Biochemistry and Biophysics and of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA. vinograd.upenn@gmail.com.ORCID http://orcid.org/0000-0002-0431-9866
Tatiana V EsipovaDepartments of Biochemistry and Biophysics and of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA. vinograd.upenn@gmail.com.ORCID http://orcid.org/0000-0002-1172-419X
Sergei A VinogradovDepartments of Biochemistry and Biophysics and of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA. vinograd.upenn@gmail.com.ORCID http://orcid.org/0000-0002-4649-5534
Damiano GenoveseDepartment of Chemistry "Giacomo Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy. enrico.rampazzo@unibo.it luca.prodi@unibo.it.ORCID http://orcid.org/0000-0002-4389-7247
Nelsi ZaccheroniDepartment of Chemistry "Giacomo Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy. enrico.rampazzo@unibo.it luca.prodi@unibo.it.ORCID http://orcid.org/0000-0002-4517-6611
Enrico RampazzoDepartment of Chemistry "Giacomo Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy. enrico.rampazzo@unibo.it luca.prodi@unibo.it.ORCID http://orcid.org/0000-0003-2290-859X
Luca ProdiDepartment of Chemistry "Giacomo Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy. enrico.rampazzo@unibo.it luca.prodi@unibo.it.ORCID http://orcid.org/0000-0002-1630-8291

Funding

Dendritic upconverting nanoparticles for multiphoton imaging and sensingR01EB018464 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI VINOGRADOV, SERGEI · 2014 to 2017
$1.5M
Enabling widespread use of high resolution imaging of oxygen in the brainR24NS092986 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BOAS, DAVID A, VINOGRADOV, SERGEI · 2015 to 2018
$1.2M
A molecular probe for high-resolution dual imaging of temperature and oxygen in vivoR21EB027397 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI VINOGRADOV, SERGEI · 2018 to 2019
$464k
NIBIB NIH HHS R01 EB018464NIBIB NIH HHS R21 EB027397NINDS NIH HHS R24 NS092986
6 · The paper itself

Abstract

Silica nanoparticles (NPs) are versatile nanomaterials, which are safe with respect to biomedical applications, and therefore are highly investigated. The advantages of NPs include their ease of preparation, inexpensive starting materials and the possibility of functionalization or loading with various doping agents. However, the solubility of the doping agent(s) imposes constraints on the choice of the reaction system and hence limits the range of molecules that can be included in the interior of NPs. To overcome this problem, herein, we improved the current state of the art synthetic strategy based on Pluronic F127 by enabling the synthesis in the presence of large amounts of organic solvents. The new method enables the preparation of nanoparticles doped with large amounts of water-insoluble doping agents. To illustrate the applicability of the technology, we successfully incorporated a range of phosphorescent metalloporphyrins into the interior of NPs. The resulting phosphorescent nanoparticles may exhibit potential for biological oxygen sensing.

Identifiers

PMID31011734
PMCPMC6739172

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.