ArticleAdvances in radiation oncology
Improvements in CBCT Image Quality Using a Novel Iterative Reconstruction Algorithm: A Clinical Evaluation.
Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed.
- HyperSight CBCT image quality and metal artifact reduction for adaptive head and neck radiotherapy: Results from a prospective clinical trial.Journal of applied clinical medical physics · 2025Trial
- Evaluation of online dose-guided adaptive fractionation for intact prostate radiotherapy.Journal of applied clinical medical physics · 2026Article
- Determining Individualized Prognosis of Head and Neck Squamous Cell Carcinoma Patients Treated with Radiotherapy Using a Prediction Model Based on Body Composition Features: Introducing a Probability Calculator.Journal of imaging informatics in medicine · 2026Article
- Towards adaptive radiotherapy: Comparing HyperSight and standard CBCT reconstructions on a C-Arm Linac.Journal of applied clinical medical physics · 2026Article
- Auto-segmentation and dose accuracy evaluation of synthetic computed tomography generated from pelvis cone-beam computed tomography images using a cycle-generative adversarial network with a novel loss function.Physics and imaging in radiation oncology · 2026Article
- Feasibility of reusing online-generated treatment plans for adaptive radiotherapy in prostate cancer.Physics and imaging in radiation oncology · 2026Article
- Assessment of TrueBeam kV Cone-Beam CT Image Quality and the Clinical Impact of Calibration Drift.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Mechanically assisted non-invasive ventilation for liver SABR: Improve CBCT, treat more accurately.Clinical and translational radiation oncology · 2025Article
- Embracing the Future of Clinical Trials in Radiation Therapy: An NRG Oncology CIRO Technology Retreat Whitepaper on Pioneering Technologies and AI-Driven Solutions.International journal of radiation oncology, biology, physics · 2025Review
- Dose calculation accuracy of clinical radiotherapy plans using next generation cone beam computed tomography imaging technology.Physics and imaging in radiation oncology · 2025Article
- Development of an automated CBCT-based simulation-free platform for expedited palliative radiotherapy on a conventional linear accelerator.Journal of applied clinical medical physics · 2025Article
- Article
- Comprehensive Image Quality Evaluation and Motion Phantom Studies of an Ultra-Fast (6-Second) Cone-Beam Computed Tomography Imaging System on a Ring Gantry Linear Accelerator.Advances in radiation oncology · 2025Article
- Uncertainty estimation in female pelvic synthetic computed tomography generated from iterative reconstructed cone-beam computed tomography.Physics and imaging in radiation oncology · 2025Article
- Evaluation of a Metal Artifact Reduction Algorithm for Image Reconstruction on a Novel CBCT Platform.Journal of applied clinical medical physics · 2024Article
- Evaluation of a Vendor-Agnostic Deep Learning Model for Noise Reduction and Image Quality Improvement in Dental CBCT.Diagnostics (Basel, Switzerland) · 2024Article
- Evaluation of knowledge-based planning models for male pelvic CBCT-based online adaptive radiotherapy on conventional linear accelerators.Journal of applied clinical medical physics · 2024Article
- The Impact of AI on Metal Artifacts in CBCT Oral Cavity Imaging.Diagnostics (Basel, Switzerland) · 2024Article
- The effects of distance between the imaging isocenter and brain center on the image quality of cone-beam computed tomography for brain stereotactic irradiation.Physical and engineering sciences in medicine · 2024Article
- Increasing the efficiency of cone-beam CT based delta-radiomics using automated contours to predict radiotherapy-related toxicities in prostate cancer.Scientific reports · 2024Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to evaluate the clinical utility of a novel iterative cone beam computed tomography (CBCT) reconstruction algorithm for prostate and head and neck (HN) cancer. METHODS AND MATERIALS: A total of 10 patients with HN and 10 patients with prostate cancer were analyzed. For each patient, raw CBCT acquisition data were used to reconstruct images with a currently available algorithm (FDK_CBCT) and novel iterative algorithm (Iterative_CBCT). Quantitative contouring variation analysis was performed using structures delineated by several radiation oncologists. For prostate, observers contoured the prostate, proximal 2 cm seminal vesicles, bladder, and rectum. For HN, observers contoured the brain stem, spinal canal, right-left parotid glands, and right-left submandibular glands. Observer contours were combined to form a reference consensus contour using the simultaneous truth and performance level estimation method. All observer contours then were compared with the reference contour to calculate the Dice coefficient, Hausdorff distance, and mean contour distance (prostate contour only). Qualitative image quality analysis was performed using a 5-point scale ranging from 1 (much superior image quality for Iterative_CBCT) to 5 (much inferior image quality for Iterative_CBCT).
resultsThe Iterative_CBCT data sets resulted in a prostate contour Dice coefficient improvement of approximately 2.4% (
conclusionsObservers noted an improvement in image uniformity, noise level, and overall image quality for Iterative_CBCT data sets. In addition, expert observers displayed an improved ability to consistently delineate soft tissue structures, such as the prostate and parotid glands. Thus, the novel iterative reconstruction algorithm analyzed in this study is capable of improving the visualization for prostate and HN cancer image guided radiation therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.