ArticleCurrent epidemiology reports2018
Use of age-period-cohort analysis in cancer epidemiology research.
Article in Current epidemiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of methods to estimate colorectal cancer incidence using population-based cancer registries.BMC medical research methodology · 2022Pooled it
- Global and Chinese burden of three major non-communicable diseases attributable to high BMI: trends from 1990 to 2021 and projections to 2050.Tropical medicine and health · 2026Article
- Evolution of birth-cohort patterns in lifestyle-associated cancer mortality across high-income countries.International journal of epidemiology · 2026Article
- Article
- Temporal trends in the probability of melanoma diagnosis in four Nordic countries, 1973-1999.Cancer causes & control : CCC · 2026Article
- Life course socioeconomic determinants of multimorbidity in later life: longitudinal evidence from the Health and Retirement Study.Longitudinal and life course studies : international journal · 2026Article
- Systematic analysis of global trends in otitis media burden across Socio-Demographic Index levels, 1990-2021: findings from the global burden of disease study 2021.Frontiers in public health · 2026Article
- Global trends, age-period-cohort analysis, and future projections of diarrhea burden: Findings from the Global Burden of Disease Study 2021.Biosafety and health · 2025Article
- Trends and the Age-Period-Cohort Effects on Mortality of Breast Cancer Among Iranian Women from 1990 to 2021.Archives of Iranian medicine · 2025Article
- Trends and inequalities in the global burden of alzheimer's disease and other dementias, 1990-2021: a Chinese perspective.BMC public health · 2025Article
- Trends and projections in cervical cancer incidence in northern Tunisia (1994-2040).BMC cancer · 2025Article
- Global temporal trends and projections of gastroesophageal reflux disease prevalence: Age-period-cohort analysis 2021.PloS one · 2025Article
- Nationwide trends and incidence of blindness in patients with diabetic retinopathy identified using an age-period-cohort analysis.Eye (London, England) · 2025Article
- Temporal trends and demographic influences on protein-energy malnutrition in China: a comprehensive analysis from 1990 to 2021.Frontiers in nutrition · 2025Article
- Ischemic heart disease burden attributable to inadequate omega-3 fatty acid intake in Chinese adults, 1990-2021: an Age-Period-Cohort analysis of the Global Burden of Disease study.Frontiers in nutrition · 2025Article
- Trends and projections of smoking-attributable ischemic stroke mortality in China, 1990-2035: a global burden of disease study.Frontiers in neurology · 2025Article
- Impact of high body mass index on gallbladder and biliary tract cancer burden in China: a comprehensive analysis of trends from 1990 to 2021.World journal of surgical oncology · 2024Article
- Trends in uterine cancer incidence in the United States: The contribution of age, period and cohort effects.Gynecologic oncology · 2024Article
- Growing old and being old: Emotional well-being across adulthood.Journal of personality and social psychology · 2023Article
- Temporal Pattern and Age-Period-Cohort Analysis of Breast Cancer Incidence in Iranian Women (2009-2017).Archives of Iranian medicine · 2023Article
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2 authors.
Funding
Abstract
purpose of reviewAge-period-cohort (APC) models simultaneously estimate the effects of age - biological process of aging; time period - secular trends that occur in all ages simultaneously; and birth cohort - variation among those born around the same year or from one generation to the next. APC models inform understanding of cancer etiology, natural history, and disparities. We reviewed findings from recent studies (published 2008-2018) examining age, period, and cohort effects and summarized trends in age-standardized rates and age-specific rates by birth cohort. We also described prevalence of cancer risk factors by time period and birth cohort, including obesity, current smoking, human papilloma virus (HPV), and hepatitis C virus (HCV). RECENT
findingsStudies (n=29) used a variety of descriptive analyses and statistical models to document age, period, and cohort trends in cancer-related outcomes. Cohort effects predominated, particularly in breast, bladder, and colorectal cancers, whereas period effects were more variable. No effect of time period was observed in studies of breast, bladder, and oral cavity cancers. Age-specific prevalence of obesity, current smoking, HPV, and HCV also varied by birth cohort, which generally paralleled cancer incidence and mortality rates. SUMMARY: We observed strong cohort effects across multiple cancer types and less consistent evidence supporting the effect of time period. Birth cohort effects point to exposures early in life - or accumulated across the life course - that increase risk of cancer. Birth cohort effects also illustrate the importance of reconsidering the timing and duration of well-established risk factors to identify periods of exposure conferring the greatest risk.
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