ArticleJournal of animal science and biotechnology2019
Effects of restrictions on maternal feed intake on the immune indexes of umbilical cord blood and liver Toll-like receptor signaling pathways in fetal goats during pregnancy.
Article in Journal of animal science and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Multi-omic analysis reveals that theAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Article
- Maternal undernutrition alters the skeletal muscle development and methylation of myogenic factors in goat offspring.Animal bioscience · 2022Article
- High-Throughput Sequencing Reveals Transcriptome Signature of Early Liver Development in Goat Kids.Genes · 2022Article
- Maternal intake restriction programs the energy metabolism, clock circadian regulator and mTOR signals in the skeletal muscles of goat offspring probably via the protein kinase A-cAMP-responsive element-binding proteins pathway.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
- Dietary rumen-protected L-arginine orAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
- Article
- 1,25-dihydroxyvitamin DBMC oral health · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundLiver has important immune function during fetal development and after birth. However, the effect of maternal malnutrition on immune function of the fetal liver is rarely reported. In this study, twelve pregnant goats (Xiangdong black goat, at d 45 of gestation) were assigned to the control group (fed 100% of nutritional requirements) and the restriction group (fed 60% of the intake of the control group) during gestation from d 55 to 100. Fetal goats were harvested at d 100 of gestation and immune indexes and amino acid profiles of the umbilical cord blood and liver Toll-like receptors (TLRs) signaling pathways were measured.
resultsMaternal body weight in the restriction group was lower than the control group (
conclusionsThese results revealed that the restriction of maternal feed intake influenced the development of heart and hepatic protein synthesis at the acute phase of fetal goats and upregulated the mRNA expression of genes involved in MyD88-dependent signaling pathways and of target cytokines.
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