Observational studyAntimicrobial resistance and infection control2019
The association between adherence to national antibiotic guidelines and mortality, readmission and length of stay in hospital inpatients: results from a Norwegian multicentre, observational cohort study.
Observational study in Antimicrobial resistance and infection control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 46 citations in OpenAlex.
- Determinants of non-adherence to antibiotic treatment guidelines in hospitalized adults with suspected community-acquired pneumonia: a prospective study.Antimicrobial resistance and infection control · 2024Trial
- An Innovative Telemedical Network to Improve Infectious Disease Management in Critically Ill Patients and Outpatients (TELnet@NRW): Stepped-Wedge Cluster Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Impact of an integrated electronic Clinical Decision Support System with proactive Antimicrobial Stewardship Feedback on prescribing appropriateness: a 2-year single-centre time-series analysis.JAC-antimicrobial resistance · 2026Article
- EMERGE: Early antiMicrobial stEwaRdship for GEneral medicine patients-targeting inpatient intravenous therapy greater than 24 hours.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Quality of Care for Hypertension in Primary Health Care in South Africa: Cross-Sectional Feasibility Study.Healthcare (Basel, Switzerland) · 2025Article
- Impact of the ABxSG Mobile Application on Antibiotic Prescribing: An Interrupted Time Series Study.Antibiotics (Basel, Switzerland) · 2025Article
- Compliance with antimicrobial stewardship guidelines in surgery: an observational, multidisciplinary, cohort study.World journal of emergency surgery : WJES · 2025Observational
- Antimicrobial stewardship principles in the evaluation of empirical carbapenem antibiotics in a private hospital in South Africa.JAC-antimicrobial resistance · 2025Article
- Respiratory quotient as an early predictor of length of stay after cardiac surgery: A prospective observational study.Asia Pacific journal of clinical nutrition · 2025Observational
- Observational
- Medication Adherence During Pregnancy: A Hospital-Based Cross-Sectional Study in Bandung, Indonesia.Patient preference and adherence · 2025Article
- Patterns of In-patient Antibiotic Use among COVID-19 Patients in a Tertiary Government Hospital: A Retrospective Cross-sectional Survey.Acta medica Philippina · 2025Article
- Paediatric Escherichia coli urinary tract infection: susceptibility trends and clinical management-a retrospective analysis of a 10-year period.Irish journal of medical science · 2024Article
- A national antimicrobial guide with local, customizable versions: how is it used? A two-year analysis.JAC-antimicrobial resistance · 2023Article
- Antibiotic prescribing to inpatients in Limpopo, South Africa: a multicentre point-prevalence survey.Antimicrobial resistance and infection control · 2023Article
- Using Culture Sensitivity Reports to Optimize Antimicrobial Therapy: Findings and Implications of Antimicrobial Stewardship Activity in a Hospital in Pakistan.Medicina (Kaunas, Lithuania) · 2023Observational
- Investigating the Effect of Adherence to Antipsychotic Therapy on the Length of Stay and Number of Hospitalizations in Patients with Schizophrenia - A Descriptive Analysis.Patient preference and adherence · 2023Article
- Antibiotic prescribing behavior among physicians in Asia: a multinational survey.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Antimicrobial therapy of community-acquired pneumonia during stewardship efforts and a coronavirus pandemic: an observational study.BMC pulmonary medicine · 2022Observational
- Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
Abstract
Background: Clinical antibiotic prescribing guidelines are essential in defining responsible use in the local context. Our objective was to investigate the association between adherence to national antibiotic prescribing guidelines and patient outcomes across a wide range of infectious diseases in hospital inpatients. Methods: Over five months in 2014, inpatients receiving antibiotics under the care of pulmonary medicine, infectious diseases and gastroenterology specialties across three university hospitals in Western Norway were included in this observational cohort study. Patient and antibiotic prescribing data gathered from electronic medical records included indication for antibiotics, microbiology test results, discharge diagnoses, length of stay (LOS), comorbidity, estimated glomerular filtration rate (eGFR) on admission and patient outcomes (primary: 30-day mortality; secondary: in-hospital mortality, 30-day readmission and LOS). Antibiotic prescriptions were classified as adherent or non-adherent to national guidelines according to documented indication for treatment. Patient outcomes were analysed according to status for adherence to guidelines using multivariate logistic, linear and competing risk regression analysis with adjustments made for comorbidity, age, sex, indication for treatment, seasonality and whether the patient was admitted from an institution or not. Results: In total, 1756 patients were included in the study. 30-day-mortality and in-hospital mortality were lower (OR = 0.48, Conclusions: Adhering to antibiotic guidelines when treating infections in hospital inpatients was associated with favourable patient outcomes in terms of mortality and LOS.
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