ArticleWorld journal of gastroenterology2019
Chronic functional constipation is strongly linked to vitamin D deficiency.
Article in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 56 citations in OpenAlex.
- Trial
- Beyond anemia: a comprehensive analysis of iron deficiency symptoms in women and their correlation with biomarkers.BMC women's health · 2025Article
- Association Between Caffeine Intake and Stool Frequency- or Consistency-Defined Constipation: Data From the National Health and Nutrition Examination Survey 2005-2010.Journal of neurogastroenterology and motility · 2025Article
- Screening of vitamin D deficiency in children with chronic functional constipation.Przeglad gastroenterologiczny · 2025Article
- Associations between feeding patterns and clinical outcomes of Hirschsprung's disease after surgery: propensity score matching approach.Frontiers in nutrition · 2025Article
- Association between dietary vitamin B2 intake and constipation: a nationwide cross-sectional study.Frontiers in medicine · 2025Article
- Evaluating the link between the dietary intake of vitamin B and constipation: a population-based study.Frontiers in nutrition · 2025Article
- Article
- Effect of Physical Activity on the Association Between Diet and Constipation: Evidence From the National Health and Nutrition Examination Survey 2007-2010.Journal of neurogastroenterology and motility · 2024Article
- Bowel function and inflammation: Is motility the other side of the coin?World journal of gastroenterology · 2024Article
- Association between dietary vitamin E intake and constipation: NHANES 2005-2010.Frontiers in nutrition · 2024Article
- Association between dietary vitamin B6 intake and constipation: a population-based study.Frontiers in nutrition · 2024Review
- A survey on functional constipation and its risk factors in older people in Shahreza, Iran.Journal of education and health promotion · 2024Article
- The consumption of dietary supplements in Saudi Arabia during the COVID-19 pandemic: A cross-sectional study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Causal associations of 25-hydroxyvitamin D with functional gastrointestinal disorders: a two-sample Mendelian randomization study.Genes & nutrition · 2023Article
- GI factors, potential to predict prostate motion during radiotherapy; a scoping review.Clinical and translational radiation oncology · 2023Article
- Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature.World journal of gastroenterology · 2023Review
- The Efficacious Benefit of 25-Hydroxy Vitamin D to Prevent COVID-19: An In-Silico Study Targeting SARS-CoV-2 Spike Protein.Nutrients · 2022Article
- The Crosstalk between Vitamin D and Pediatric Digestive Disorders.Diagnostics (Basel, Switzerland) · 2022Review
- Vitamin D and COVID-19: is there a role?Journal of diabetes and metabolic disorders · 2021Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have examined intestinal motility disorders, which are disabling conditions associated with chronic functional constipation, whose pathogenesis is actually not well-defined.
aimTo investigate the relationship between serum 25-hydroxyvitamin D levels and functional chronic constipation associated to intestinal motility disorders.
methodsWe performed a prospective case-control study, from May-June to November 2017. Glucose/lactulose breath tests, radiopaque markers (multiple capsule techniques) and wireless motility capsule analysis were used to assess colonic and oro-cecal transit time, after excluding small-intestinal bacterial overgrowth condition. Then, we measured 25-hydroxyvitamin D levels in patients with intestinal motility disorders and we further evaluated the influence of intestinal motility disorders on psychological symptoms/quality of life using validated questionnaires, the Irritable Bowel Syndrome Quality of life (IBS-QOL), the Short Form Health Survey 12, and the Hospital Anxiety and Depression Scale 14 (HADS-14 A and HADS-14 D).
resultsWe enrolled 86 patients with chronic functional constipation associated to intestinal motility disorders and 86 matched healthy subjects. Patients with intestinal motility disorders had lower 25-hydroxyvitamin D levels (
conclusionVitamin D deficiency, anxiety and depression symptoms are commonly associated with chronic functional constipation induced by intestinal motility disorders. Vitamin D serum levels should be routinely measured in these patients.
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