ReviewGeriatrics (Basel, Switzerland)2018
Systematic Review of Pharyngeal and Esophageal Manometry in Healthy or Dysphagic Older Persons (>60 years).
Review in Geriatrics (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Pooled it
- Examining the Use of Pill Swallowing in Dysphagia Assessment: A Survey of Common Practices.Dysphagia · 2026Article
- The Impact of Rheological Characteristics on the Swallowing Dynamics of Xanthan Gum-Based Thickeners.Foods (Basel, Switzerland) · 2026Article
- Esophageal Dysfunction in Immune Checkpoint Inhibitor-related Myositis.Internal medicine (Tokyo, Japan) · 2025Article
- Age-defying swallowing.Frontiers in aging · 2025Review
- Gastrointestinal Motility Function and Dysfunction in the Elderly Patient: What Are the Effects of Aging?Visceral medicine · 2024Review
- Speech-Swallow Dissociation of Velopharyngeal Incompetence with Pseudobulbar Palsy: Evaluation by High-Resolution Manometry.Dysphagia · 2024Article
- Clinical and high-resolution manometry of 801 patients with esophageal dysmotility, including achalasia, in relation to age.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Correlation of deglutitive striated esophagus motor function and pharyngeal phase swallowing biomechanical events.Neurogastroenterology and motility · 2024Article
- Additional Diagnostic Yield of the Rapid Drink Challenge in Chicago Classification Version 4.0 Compared With Version 3.0.Journal of neurogastroenterology and motility · 2024Article
- Normative High-Resolution Pharyngeal Manometry: Impact of Age, Size of System, and Sex on Primary Metrics and Pressure Stability.Dysphagia · 2024Article
- Article
- An Uncommon Case of Weight Loss in a Nonagenarian.Annals of geriatric medicine and research · 2023Article
- Analysis of the clinical characteristics of dabigatran-induced oesophagitis.European journal of hospital pharmacy : science and practice · 2023Article
- Differences in upper esophageal sphincter function and clinical characteristics among the three subtypes of Japanese patients with esophageal achalasia.Esophagus : official journal of the Japan Esophageal Society · 2022Article
- Applying High-Resolution Impedance Manometry for Detecting Swallowing Change in Anterior Cervical Spine Surgery Patients.Frontiers in surgery · 2022Article
- Article
- Diagnosis and treatments for oropharyngeal dysphagia: effects of capsaicin evaluated by newly developed ultrasonographic method.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2020Review
- Dysphagia in Frail Patients Is Not Frailty Dysphagia.Geriatrics (Basel, Switzerland) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We undertook a systematic review of swallowing biomechanics, as assessed using pharyngeal and esophageal manometry in healthy or dysphagic older individuals aged over 60 years of age, comparing findings to studies of younger participants. PRISMA-P methodology was used to identify, select, and evaluate eligible studies. Across studies, older participants had lower upper esophageal sphincter (UES) resting pressures and evidence of decreased UES relaxation when compared to younger groups. Intrabolus pressures (IBP) above the UES were increased, demonstrating flow resistance at the UES. Pharyngeal contractility was increased and prolonged in some studies, which may be considered as an attempt to compensate for UES flow resistance. Esophageal studies show evidence of reduced contractile amplitudes in the distal esophagus, and an increased frequency of failed peristaltic events, in concert with reduced lower esophageal sphincter relaxation, in the oldest subjects. Major motility disorders occurred in similar proportions in older and young patients in most clinical studies, but some studies show increases in achalasia or spastic motility in older dysphagia and noncardiac chest pain patients. Overall, study qualities were moderate with a low likelihood of bias. There were few clinical studies specifically focused on swallowing outcomes in older patient groups and more such studies are needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.