Evidence map›Paper›PMID 31010894›Full record

ArticleOccupational and environmental medicine2019

Effects of occupational exposure to respirable quartz dust on acute myocardial infarction.

Johannes Gellissen, Dagmar Pattloch, Matthias Möhner

Open access · hybridAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Johannes GellissenWork and Health, Federal Institute for Occupational Safety and Health, Berlin, Germany.
Dagmar PattlochWork and Health, Federal Institute for Occupational Safety and Health, Berlin, Germany.
Matthias MöhnerWork and Health, Federal Institute for Occupational Safety and Health, Berlin, Germany.ORCID 0000-0003-3225-5879
Federal Institute for Occupational Safety and Health · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study is to investigate the effects of occupational exposure to respirable quartz (RQ) on first acute myocardial infarction (AMI). RQ causes pulmonary diseases like silicosis and has also been linked to cardiovascular diseases. Inflammation is hypothesised as the underlying pathway.

methodsWe performed a 1:3 matched case-control study nested in a cohort of male uranium miners. We included cases (identified from hospital records and validated according to WHO criteria) who had suffered their first AMI while still employed and <65 years of age. Controls were matched by date of birth and Wismut recruitment era. RQ exposure was derived from a job-exposure matrix. We performed a conditional logistic regression adjusted for smoking, metabolic syndrome and baseline erythrocyte sedimentation rate. Subgroups by date of birth and Wismut recruitment era were analysed to minimise the impact of pre-exposures.

resultsThe study base comprised 292 matched sets. The cumulative exposure ranged from 0 to 38.9 mg/m

conclusionsAn impact of quartz dust on first AMI was observed only in a small subgroup that had virtually no pre-exposure to RQ. Further studies on the basis of complete occupational history are required to substantiate this finding.

Indexed as

AdultCase-Control StudiesCohort StudiesDustFemaleGermanyHumansInhalation ExposureLogistic ModelsMaleMiddle AgedMinersMyocardial InfarctionOccupational ExposureQuartzSilicosisDustQuartzacute myocardial infarctiondustsepidemiologynested case–control studyrespirable quartz

Identifiers

PMID31010894
PMCPMC6585272
OpenAlexW2941606320

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.