Evidence map›Paper›PMID 31010876›Full record

Trial reportDiabetes care2019

Prevalence and Prognosis of Unrecognized Myocardial Infarction in Asymptomatic Patients With Diabetes: A Two-Center Study With Up to 5 Years of Follow-up.

Michael D Elliott, John F Heitner, Han Kim, Edwin Wu, Michele A Parker, Daniel C Lee, Dixon B Kaufman, Robert O Bonow, Robert Judd, Raymond J Kim

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Diabetes care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  12. A large asymptomatic postinfarction left ventricular pseudoaneurysm - an incidental finding during a recurrent coronary event.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2023
    Article
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  18. MIKB: A manually curated and comprehensive knowledge base for myocardial infarction.Computational and structural biotechnology journal · 2021
    Article
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Michael D ElliottDuke Cardiovascular Magnetic Resonance Center and Division of Cardiology, Duke University Medical Center, Durham, NC michael.elliott@atriumhealth.org.ORCID 0000-0002-9057-3915
John F HeitnerDuke Cardiovascular Magnetic Resonance Center and Division of Cardiology, Duke University Medical Center, Durham, NC.
Han KimDuke Cardiovascular Magnetic Resonance Center and Division of Cardiology, Duke University Medical Center, Durham, NC.
Edwin WuDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Michele A ParkerDuke Cardiovascular Magnetic Resonance Center and Division of Cardiology, Duke University Medical Center, Durham, NC.
Daniel C LeeDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Dixon B KaufmanDivision of Organ Transplantation, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
Robert O BonowDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Robert JuddDuke Cardiovascular Magnetic Resonance Center and Division of Cardiology, Duke University Medical Center, Durham, NC.
Raymond J KimDuke Cardiovascular Magnetic Resonance Center and Division of Cardiology, Duke University Medical Center, Durham, NC.
Duke Medical Center · USNorthwestern University · US

Funding

Delayed-Enhancement Cardiac MRI: Prognostic Implications and Improved ImagingR01HL064726 · NHLBI · NORTHWESTERN UNIVERSITY · PI KIM, RAYMOND J · 2001 to 2014
$4.1M
NHLBI NIH HHS R01 HL064726
6 · The paper itself

Abstract

objectiveTo determine the prevalence and prognostic significance of unrecognized myocardial infarction (MI) by delayed-enhancement MRI (DE-MRI) in asymptomatic patients with diabetes. RESEARCH DESIGN AND

methodsIn this prospective, two-center study of asymptomatic patients without known cardiac disease (

resultsOverall, the prevalence of unrecognized MI was 19% by DE-MRI (28% high-risk group and 13% average-risk group) and 5% by electrocardiography. During up to 5 years of follow-up with a total of 460 patient-years of follow-up, the rate of death/MI was markedly higher in patients with diabetes with (vs. without) unrecognized MI (all 44% vs. 7%, high-risk group 43% vs. 6%, and average-risk group 44% vs. 8%; all

conclusionsUnrecognized MI is prevalent in asymptomatic patients with diabetes without a history of cardiac disease and confers a markedly increased risk of death and clinical MI.

Indexed as

AdultAgedAsymptomatic DiseasesCase-Control StudiesCohort StudiesDiabetes Mellitus, Type 2Diabetic AngiopathiesElectrocardiographyFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionPrevalence

Identifiers

PMID31010876
PMCPMC6973647
OpenAlexW2940086844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.