Evidence map›Paper›PMID 31010869›Full record

ArticleAntimicrobial agents and chemotherapy2019

Natamycin and Voriconazole Exhibit Synergistic Interactions with Nonantifungal Ophthalmic Agents against

Christiaan A Rees, Ruina Bao, Michael E Zegans, Robert A Cramer

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Propranolol is efficacious againstAntimicrobial agents and chemotherapy · 2025
    Article
  3. Article
  4. Article
  5. Update on the management of fungal keratitis.International ophthalmology · 2021
    Review
  6. Article
  7. MultiresistantInfection and drug resistance · 2019
    Review
  8. Emerging treatments in fungal keratitis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christiaan A ReesDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Ruina BaoDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Michael E Zegans *Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Robert A Cramer *Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA Robert.A.Cramer.JR@dartmouth.edu.
Dartmouth College · USDartmouth–Hitchcock Medical Center · US

Funding

Fungal virulence factors during corneal infectionsR21EY028677 · NEI · DARTMOUTH-HITCHCOCK CLINIC · PI FULLER, KEVIN K., ZEGANS, MICHAEL ERIC · 2018 to 2019
$448k
NEI NIH HHS R21 EY028677
6 · The paper itself

Abstract

The

Indexed as

Antifungal AgentsDrug SynergismEye Infections, FungalFungiFusariumHumansItraconazoleMicrobial Sensitivity TestsNatamycinVoriconazoleAntifungal AgentsItraconazoleNatamycinVoriconazoleantifungal susceptibility testingfungal keratitisFusariumocular

Identifiers

PMID31010869
PMCPMC6591621
OpenAlexW2950572270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.