Evidence map›Paper›PMID 31010866›Full record

ArticleAntimicrobial agents and chemotherapy2019

Isoniazid Resistance in

Arash Ghodousi, Elisa Tagliani, Eranga Karunaratne, Stefan Niemann, Jennifer Perera, Claudio U Köser, Daniela Maria Cirillo

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance.Journal of clinical tuberculosis and other mycobacterial diseases · 2023
    Article
  7. Article
  8. Clinical standards for the dosing and management of TB drugs.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Article
  9. Article
  10. Article
  11. Correlating genetic mutations with isoniazid phenotypic levels of resistance in Mycobacterium tuberculosis isolates from patients with drug-resistant tuberculosis in a high burden setting.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  12. Article
  13. Detection of genomic mutations inNew microbes and new infections · 2021
    Article
  14. Article
  15. Article
  16. Individualized Treatment of Multidrug-resistant Tuberculosis Using Whole-Genome Sequencing and Expanded Drug-Susceptibility Testing.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  17. Initial resistance to companion drugs should not be considered an exclusion criterion for the shorter multidrug-resistant tuberculosis treatment regimen.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  18. Clarity with INHindsight: High-Dose Isoniazid for Drug-Resistant Tuberculosis withAmerican journal of respiratory and critical care medicine · 2020
    Article
  19. Integrating Pharmacokinetics and Pharmacodynamics in Operational Research to End Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arash GhodousiEmerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0001-9334-1573
Elisa TaglianiEmerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Eranga KarunaratneFaculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Stefan NiemannMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.
Jennifer PereraFaculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Claudio U Köser *Department of Genetics, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-0232-846X
Daniela Maria Cirillo *Emerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy cirillo.daniela@hsr.it.ORCID 0000-0001-6415-1535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MIC testing using the Bactec mycobacteria growth indicator tube system 960 of 70 phylogenetically diverse, isoniazid-resistant clinical strains of

Indexed as

Antitubercular AgentsDrug Resistance, BacterialIsoniazidMicrobial Sensitivity TestsMycobacterium tuberculosisWhole Genome SequencingAntitubercular AgentsIsoniazidisoniazid resistanceMGIT 960MICMycobacterium tuberculosiswhole-genome sequencing

Identifiers

PMID31010866
PMCPMC6591585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.