Evidence map›Paper›PMID 31010718›Full record

ArticleKidney international2019

Comparison of organ donation and transplantation rates between opt-out and opt-in systems.

Adam Arshad, Benjamin Anderson, Adnan Sharif

Erratum issuedOpen access · bronzeAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Kidney international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
38.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 280 citations in OpenAlex.

  1. Public Opinions on Removing Disincentives and Introducing Incentives for Organ Donation: Proposing a European Research Agenda.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Pooled it
  2. Donor heart selection: Evidence-based guidelines for providers.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Guideline
  3. Review
  4. Review
  5. Does opt-out legislation crowd out living organ donations? A cross-country study.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  6. Potential for donation after circulatory death in Germany: a multicenter retrospective study at seven university hospitals.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Hospital-Related Determinants of Refusal of Organ Donation in France: A Multilevel Study.International journal of environmental research and public health · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Expanding the Donor Pool.Methodist DeBakey cardiovascular journal · 2025
    Review
  15. Article
  16. Promoting and Supporting Positive Conversations and Knowledge Mobilisation About Organ Donation in NHS Staff: a Hashtag "#" Series of Projects.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Adam ArshadCollege of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Benjamin AndersonDepartment of Nephrology and Transplantation, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK.
Adnan SharifDepartment of Nephrology and Transplantation, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK. Electronic address: adnan.sharif@uhb.nhs.uk.
Queen Elizabeth Hospital · GBQueen Elizabeth Hospital Birmingham · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies comparing opt-out and opt-in approaches to organ donation have generally suggested higher donation and transplantation rates in countries with an opt-out strategy. We compared organ donation and transplantation rates between countries with opt-out versus opt-in systems to investigate possible differences in the contemporary era. Data were analysed for 35 countries registered with the Organisation for Economic Co-operation and Development (17 countries classified as opt-out, 18 classified as opt-in) and obtained organ donation and transplantation rates for 2016 from the Global Observatory for Donation and Transplantation. Compared to opt-in countries, opt-out countries had fewer living donors per million population (4.8 versus 15.7, respectively) with no significant difference in deceased donors (20.3 versus 15.4, respectively). Overall, no significant difference was observed in rates of kidney (35.2 versus 42.3 respectively), non-renal (28.7 versus 20.9, respectively), or total solid organ transplantation (63.6 versus 61.7, respectively). In a multivariate linear regression model, an opt-out system was independently predictive of fewer living donors but was not associated with the number of deceased donors or with transplantation rates. Apart from the observed difference in the rates of living donation, our data demonstrate no significant difference in deceased donation or solid organ transplantation activity between opt-out versus opt-in countries. This suggests that other barriers to organ donation must be addressed, even in settings where consent for donation is presumed.

Indexed as

Cross-Cultural ComparisonHumansOrgan TransplantationPresumed ConsentTissue and Organ ProcurementTissue Donorsdeceased donationliving donationopt-outorgan donationpresumed consenttransplantation

Identifiers

PMID31010718
OpenAlexW2921549192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.