Evidence map›Paper›PMID 31010667›Full record

ArticleBiophysical journal2019

Bilateral Spontaneous Otoacoustic Emissions Show Coupling between Active Oscillators in the Two Ears.

Yuttana Roongthumskul, Dáibhid Ó Maoiléidigh, A J Hudspeth

Open access · hybridAbstract read
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. How Exceptional Is the Ear?Journal of the Association for Research in Otolaryngology : JARO · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Whistling While it Works: Spontaneous Otoacoustic Emissions and the Cochlear Amplifier.Journal of the Association for Research in Otolaryngology : JARO · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Yuttana RoongthumskulHoward Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York.
Dáibhid Ó MaoiléidighHoward Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California.
A J HudspethHoward Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York. Electronic address: hudspaj@rockefeller.edu.
Howard Hughes Medical Institute · USRockefeller University · USStanford University · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Spontaneous otoacoustic emissions (SOAEs) are weak sounds that emanate from the ears of tetrapods in the absence of acoustic stimulation. These emissions are an epiphenomenon of the inner ear's active process, which enhances the auditory system's sensitivity to weak sounds, but their mechanism of production remains a matter of debate. We recorded SOAEs simultaneously from the two ears of the tokay gecko and found that binaural emissions could be strongly correlated: some emissions occurred at the same frequency in both ears and were highly synchronized. Suppression of the emissions in one ear often changed the amplitude or shifted the frequency of emissions in the other. Decreasing the frequency of emissions from one ear by lowering its temperature usually reduced the frequency of the contralateral emissions. To understand the relationship between binaural SOAEs, we developed a mathematical model of the eardrums as noisy nonlinear oscillators coupled by the air within an animal's mouth. By according with the model, the results indicate that some SOAEs are generated bilaterally through acoustic coupling across the oral cavity. The model predicts that sound localization through the acoustic coupling between ears is influenced by the active processes of both ears.

Indexed as

AnimalsEarLizardsModels, BiologicalNonlinear DynamicsOtoacoustic Emissions, SpontaneousTemperature

Identifiers

PMID31010667
PMCPMC6531668
OpenAlexW2950234413

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.