ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2019
Hematology and Clinical Chemistry Reference Intervals for Inbred Strain 13/n Guinea Pigs (
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Hemorrhagic Fever Disease in STAT-1 Knockout Mice Infected with Lujo Virus.Pathogens (Basel, Switzerland) · 2026Article
- Age- and sex-associated differences in Lujo hemorrhagic fever pathogenesis in strain 13/N guinea pigs.PLoS neglected tropical diseases · 2025Article
- Clinical value of amylase and its prognostic accuracy in guinea pigs (Cavia porcellus).The Journal of small animal practice · 2025Article
- A cross-species proteomic assessment of cost-effective platforms for depleting high-abundant proteins from blood serum.BMC methods · 2025Article
- Hematological profile of free-range Sunda porcupine (Open veterinary journal · 2024Article
- Ultraviolet light and riboflavin accelerates red blood cell dysfunction in vitro and in a guinea pig transfusion model.Blood transfusion = Trasfusione del sangue · 2024Article
- Biological Variation in Biochemistry Analytes in Laboratory Guinea Pigs (Veterinary sciences · 2023Article
- Comparison of two point of care lactate instruments in guinea pigs (Journal of exotic pet medicine · 2023Article
- Effect of Parental Age, Parity, and Pairing Approach on Reproduction in Strain 13/N Guinea Pigs (Animals : an open access journal from MDPI · 2023Article
- Effect ofFrontiers in veterinary science · 2023Article
- Targeting of a Conserved Epitope in Mouse and Human GPVI Differently Affects Receptor Function.International journal of molecular sciences · 2022Article
- ZOOMICS: Comparative Metabolomics of Red Blood Cells From Guinea Pigs, Humans, and Non-human Primates During Refrigerated Storage for Up to 42 Days.Frontiers in physiology · 2022Article
- Research-Relevant Conditions and Pathology of Laboratory Mice, Rats, Gerbils, Guinea Pigs, Hamsters, Naked Mole Rats, and Rabbits.ILAR journal · 2021Review
- Age- and sex-associated differences in hematology and biochemistry parameters of Dunkin Hartley guinea pigs (Cavia porcellus).PloS one · 2021Article
- Hematological and Serum Biochemistry Values in Free-Ranging Crested Porcupine.Veterinary sciences · 2020Article
- Prothrombin Time, Activated Partial Thromboplastin Time, and Fibrinogen Reference Intervals for Inbred Strain 13/N Guinea Pigs (Microorganisms · 2020Article
- Suboptimal Handling of Piccolo Samples or Reagent Discs for Consideration in Ebola Response.Emerging infectious diseases · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inbred Strain 13/N Guinea Pigs are Frequently Used As Animal Models in Studies of Emerging and High-pathogenicity Viruses. To Date, Clinical Reference Intervals Have Not Been Established for Hematology and Clinical Chemistry Parameters in This Strain. We Obtained Whole-blood Samples from the Cranial Vena Cava of Healthy Strain 13/N Colony Animals for Inhouse Cbc and Clinical Chemistry Analyses. Analyte Values Were Investigated to Determine Subpopulation Differences According to Age and Sex. Glucose, Albumin, Alp, Lymphocyte Percentage, Hgb, and Mchc Decreased with Age, Whereas Neutrophil and Monocyte Percentages, Bun, Creatinine, Calcium, and Amylase Increased with Age. Total Protein and Wbc Counts Increased Over the First 300 D of Life Before Stabilizing. Across All Age Categories, Female Guinea Pigs Consistently Had Lower Rbc, Hct, Hgb, Alt, Alp, and Amylase Levels and Higher Mcv Values Than Males. These Trends Were Strongest in Adults (age, 151 Through 900 D). Most Parameters Stabilized by 300 D; Previous Studies Used 60 D or 120 D As Adult Age and 90 to 120 D As Sexual Maturity. We Recommend Age Group Definitions of 0 Through 150 D for Juveniles, 151 Through 900 D for Adults, and Older Than 900 D for Geriatric Adult Strain 13/N Guinea Pigs.
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