ArticlePsychological medicine2020
Are there temporal subtypes of premenstrual dysphoric disorder?: using group-based trajectory modeling to identify individual differences in symptom change.
Article in Psychological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Biological rhythms in premenstrual syndrome and premenstrual dysphoric disorder: a systematic review.BMC women's health · 2024Pooled it
- Effects of acute estradiol and progesterone on perimenstrual exacerbation of suicidal ideation and related symptoms: a crossover randomized controlled trial.Translational psychiatry · 2022Trial
- Measuring premenstrual disorders in adolescence: prevalence of premenstrual syndrome and premenstrual dysphoric disorder and psychometric validation of the PMS-I-Y in a German-speaking sample.BMC women's health · 2026Article
- Affective Sensitivity to Ovarian Steroid Hormone Flux Across the Menstrual Cycle: Manifestations and Biopsychosocial Risk Factors.Annual review of clinical psychology · 2026Review
- Within-person associations between daily ovarian steroid levels and mood-related symptoms in ovulatory and anovulatory early adolescents.Psychoneuroendocrinology · 2026Article
- Peripheral cyclical expression of GABA-A receptor subunit genes and menstrual cycle affective change: a dimensional, transdiagnostic study.Translational psychiatry · 2025Article
- Self-Guided Mental Health Interventions for Premenstrual Mood Symptoms.Current psychiatry reports · 2025Review
- How to study the menstrual cycle as a continuous variable: Implementing phase-aligned cycle time scaling (PACTS) with the menstrualcycleR package.Psychoneuroendocrinology · 2025Article
- Toward Precision Reproductive Psychiatry: A Call for Targeted, Transdiagnostic Approaches to Premenstrual Disorders.The American journal of psychiatry · 2025Article
- Unmasking the cycle: Premenstrual and menstrual exacerbation of psychiatric disorders and impact on female mental health.World journal of psychiatry · 2025Review
- Leveraging research into sex differences and steroid hormones to improve brain health.Nature reviews. Endocrinology · 2025Review
- Article
- The Impact of the Trajectory of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio on the Incidence of Metabolic Dysfunction-Associated Fatty Liver Disease: Random Forest Anaylsis, Trajectory Anaylsis, and Mendelian Randomization Study.Journal of inflammation research · 2025Article
- Dimensional Affective Sensitivity to Hormones across the Menstrual Cycle (DASH-MC): A transdiagnostic framework for ovarian steroid influences on psychopathology.Molecular psychiatry · 2025Review
- Association Between Serum Lipid Traits and Cognitive Function in Middle-aged and Elderly Adults: A Longitudinal Study.Current Alzheimer research · 2025Article
- The trajectory of intrinsic capacity and its related factors among elderly Chinese patients with cardiovascular disease: a prospective cohort study.Frontiers in endocrinology · 2025Article
- Biomarker development for menstrual cycle affective change: the need for greater temporal, mechanistic, and phenotypic specificity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- A novel method for quantifying affective sensitivity to endogenous ovarian hormones.Psychoneuroendocrinology · 2024Article
- Associations of luteal phase changes in vagally mediated heart rate variability with premenstrual emotional changes.BMC women's health · 2024Observational
- A call to integrate menstrual cycle influences into just-in-time adaptive interventions for suicide prevention.Frontiers in psychiatry · 2024Article
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Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
Abstract
backgroundPremenstrual dysphoric disorder (PMDD) is a new Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 diagnosis characterized by the cyclical emergence of emotional and physical symptoms in the luteal phase of the menstrual cycle, with symptom remission in the follicular phase. Converging evidence highlights the possibility of distinct subtypes of PMDD with unique pathophysiologies, but temporal subgroups have yet to be explored in a systematic way.
methodsIn the current work, we use group-based trajectory modeling to identify unique trajectory subgroups of core emotional and total PMDD symptoms across the perimenstrual frame (days -14 to +9, where day 0 is menstrual onset) in a sample of 74 individuals prospectively diagnosed with DSM-5 PMDD.
resultsFor the total daily symptom score, the best-fitting model was comprised of three groups: a group demonstrating moderate symptoms only in the premenstrual week (65%), a group demonstrating severe symptoms across the full 2 weeks of the luteal phase (17.5%), and a group demonstrating severe symptoms in the premenstrual week that were slow to resolve in the follicular phase (17.5%).
conclusionsThese trajectory groups are discussed in the context of the latest work on the pathophysiology of PMDD. Experimental work is needed to test for the presence of possible pathophysiologic differences in trajectory groups, and whether unique treatment approaches are needed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.