ArticleJournal of enzyme inhibition and medicinal chemistry2019
Sesquiterpenoids and 2-(2-phenylethyl)chromones respectively acting as α-glucosidase and tyrosinase inhibitors from agarwood of an Aquilaria plant.
Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Agarwood in the Modern Era: Integrating Biotechnology and Pharmacology for Sustainable Use.International journal of molecular sciences · 2025Pooled it
- Terpene synthases screening in agarwood treeSynthetic and systems biotechnology · 2027Article
- A quarter-century journey into 4-chromone derivatives: synthesis, reactions, and pioneering applications thereof.RSC advances · 2026Review
- Anti-Inflammatory Properties of Agarwood (Aquilaria Spp.): An Integrated Review of Phytochemistry, Molecular Mechanisms, and Therapeutic Applications.Drug design, development and therapy · 2026Review
- Integrated proteomic and metabolomic analyses reveal the salt-induced agarwood formation mechanism of Aquilaria sinensis.BMC plant biology · 2025Article
- Characterization and Analysis of 2-(2-Phenylethyl)chromone Derivatives and Sesquiterpenoids from Agarwood of Four "Qi-Nan" Clones (Molecules (Basel, Switzerland) · 2025Article
- The Potential Therapeutic Use of Agarwood for Diabetes: A Scoping Review.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Review
- Anatomical, chemical and endophytic fungal diversity of a Qi-Nan clone ofFrontiers in plant science · 2024Article
- Pharmacology and therapeutic potential of agarwood and agarwood tree leaves in periodontitis.Frontiers in pharmacology · 2024Review
- Article
- Naturally-Occurring Tyrosinase Inhibitors Classified by Enzyme Kinetics and Copper Chelation.International journal of molecular sciences · 2023Review
- PotentialMarine drugs · 2023Article
- Comprehensive Comparisons between Grafted Kynam Agarwood and Normal Agarwood on Traits, Composition, and In Vitro Activation of AMPK.Molecules (Basel, Switzerland) · 2023Article
- Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: a critical review on a structure-activity relationship.Journal of enzyme inhibition and medicinal chemistry · 2022Review
- Agarwood-The Fragrant Molecules of a Wounded Tree.Molecules (Basel, Switzerland) · 2022Review
- Zizaane-Type Sesquiterpenoids and Their Rearranged Derivatives from Agarwood of anMolecules (Basel, Switzerland) · 2021Article
- Effects of various artificial agarwood-induction techniques on the metabolome of Aquilaria sinensis.BMC plant biology · 2021Article
- Concise Total Synthesis of Agarozizanol B via a Strained Photocascade Intermediate.Angewandte Chemie (International ed. in English) · 2021Article
- Genome sequence of the agarwood tree Aquilaria sinensis (Lour.) Spreng: the first chromosome-level draft genome in the Thymelaeceae family.GigaScience · 2020Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ethyl ether extract of agarwood from an Aquilaria plant afforded six new sesquiterpenoids, Agarozizanol A - F (1-6), together with four known sesquiterpenoids and six known 2-(2-phenylethyl)chromones. Their structures were elucidated via detailed spectroscopic analysis, X-ray diffraction, and comparisons with the published data. All the isolates were evaluated for the α-glucosidase and tyrosinase inhibitory activities in vitro. Compounds 5, 7, 8, and 10 showed significant inhibition of α-glucosidase with IC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.