ArticleBrain sciences2019
Reliability of Fronto-Amygdala Coupling during Emotional Face Processing.
Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of studies that used NIRS to measure neural activation during emotion processing in healthy individuals.Social cognitive and affective neuroscience · 2021Pooled it
- Amygdala activity after subchronic escitalopram administration in healthy volunteers: A pharmaco-functional magnetic resonance imaging study.Journal of psychopharmacology (Oxford, England) · 2024Trial
- Neuroimaging correlates and predictors of response to repeated-dose intravenous ketamine in PTSD: preliminary evidence.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Trial
- Opportunities and challenges in connectivity analysis for task-based fMRI comment on "connectivity analyses for task-based fMRI" by Huang S, De Brigard, F., Cabeza, R, and Davis, S.W.Physics of life reviews · 2024Article
- Amygdala fMRI-A Critical Appraisal of the Extant Literature.Neuroscience insights · 2024Review
- Anxiety Shapes Amygdala-Prefrontal Dynamics During Movie Watching.Biological psychiatry global open science · 2023Article
- Anxiety and amygdala connectivity during movie-watching.Neuropsychologia · 2022Article
- Article
- Internal reliability of blame-related functional MRI measures in major depressive disorder.NeuroImage. Clinical · 2021Article
- Predicting Response to Brain Stimulation in Depression: a Roadmap for Biomarker Discovery.Current behavioral neuroscience reports · 2021Review
- Visual cortical regions show sufficient test-retest reliability while salience regions are unreliable during emotional face processing.NeuroImage · 2020Article
- Changes in functional connectivity with cognitive behavioral therapy for social anxiety disorder predict outcomes at follow-up.Behaviour research and therapy · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
One of the most exciting translational prospects for brain imaging research is the potential use of functional magnetic resonance imaging (fMRI) 'biomarkers' to predict an individual's risk of developing a neuropsychiatric disorder or the likelihood of responding to a particular intervention. This proposal depends critically on reliable measurements at the level of the individual. Several previous studies have reported relatively poor reliability of amygdala activation during emotional face processing, a key putative fMRI 'biomarker'. However, the reliability of amygdala connectivity measures is much less well understood. Here, we assessed the reliability of task-modulated coupling between three seed regions (left and right amygdala and the subgenual anterior cingulate cortex) and the dorsomedial frontal/cingulate cortex (DMFC), measured using a psychophysiological interaction analysis in 29 healthy individuals scanned approximately two weeks apart. We performed two runs on each day of three different emotional face-processing tasks: emotion identification, emotion matching, and gender classification. We tested both between-day reliability and within-day (between-run) reliability. We found good-to-excellent within-subject reliability of amygdala-DMFC coupling, both between days (in two tasks), and within day (in one task). This suggests that disorder-relevant regional coupling may be sufficiently reliable to be used as a predictor of treatment response or clinical risk in future clinical studies.
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