Evidence map›Paper›PMID 31010183›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis and In Vitro Antibacterial Activity of Quaternized 10-Methoxycanthin-6-one Derivatives.

Na Li, Dan Liu, Jiang-Kun Dai, Jin-Yi Wang, Jun-Ru Wang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Na LiCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, Shaanxi, China. lnuk@nwsuaf.edu.cn.
Dan LiuCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling 712100, Shaanxi, China. ld127222@126.com.
Jiang-Kun DaiCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling 712100, Shaanxi, China. daijkun@hotmail.com.
Jin-Yi WangCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, Shaanxi, China. jywang@nwsuaf.edu.cn.
Jun-Ru WangCollege of Chemistry and Pharmacy, Northwest A&F University, Yangling 712100, Shaanxi, China. wangjunru@nwafu.edu.cn.ORCID 0000-0003-1967-5967

Funding

National Natural Science Foundation of China 81773603
6 · The paper itself

Abstract

backgroundBased on our previous work, we found that 10-methoxycanthin-6-one displayed potential antibacterial activity and quaternization was an available method for increasing the antibacterial activity. Here, we explored the antibacterial activity of quaternized 10-methoxy canthin-6-one derivatives. METHODS AND

resultsTwenty-two new 3-

conclusionsThis work provides two new effective quaternized canthin-6-one derivatives as candidate bactericide, promoting the development of natural-sourced bactericides and preservatives.

Indexed as

Anti-Bacterial AgentsCarbolinesIndole AlkaloidsMicrobial Sensitivity TestsPseudomonas syringaeRalstonia solanacearumStructure-Activity RelationshipAnti-Bacterial Agentscanthin-6-oneCarbolinesIndole Alkaloids10-methoxycanthin-6-oneantibacterialquaternizationSARs

Identifiers

PMID31010183
PMCPMC6514585

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.