Evidence map›Paper›PMID 31010130›Full record

ArticleInternational journal of molecular sciences2019

The Impact of

Sylwia Cyboran-Mikołajczyk, Katarzyna Solarska-Ściuk, Katarzyna Mieszała, Natalia Glatzel-Plucińska, Karolina Matczak, Halina Kleszczyńska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sylwia Cyboran-MikołajczykDepartment of Physics and Biophysics, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. sylwia.cyboran@upwr.edu.pl.
Katarzyna Solarska-ŚciukDepartment of Physics and Biophysics, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. katarzyna.solarska-sciuk@upwr.edu.pl.
Katarzyna MieszałaDepartment of Histology and Embryology, Medical University of Wroclaw, Chałubińskiego 6a, 50-368 Wrocław, Poland. katarzynamieszala@wp.pl.
Natalia Glatzel-PlucińskaDepartment of Histology and Embryology, Medical University of Wroclaw, Chałubińskiego 6a, 50-368 Wrocław, Poland. n.m.glatzel@gmail.com.ORCID 0000-0001-6901-1240
Karolina MatczakDepartment of Medical Biophysics, University of Lodz, Pomorska 141/143, 90-236 Łódź, Poland. karolina.matczak@biol.uni.lodz.pl.ORCID 0000-0002-6374-9356
Halina KleszczyńskaDepartment of Physics and Biophysics, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. halina.kleszczynska@upwr.edu.pl.
Wrocław University of Environmental and Life Sciences · PLUniversity of Wrocław · PLUniversity of Łódź · PL

Funding

Polska Akademia Nauk DEC-2017/01/X/NZ9/00908
6 · The paper itself

Abstract

With the aim of contributing to the knowledge about their potential therapeutic activity, we determined the biological activities of cyanidin and its selected O-glycosides in relation to erythrocytes (RBCs) and human dermal vascular endothelial cells (HMEC-1). Furthermore, on the basis of changes in the physical/functional properties of the cells, the structure-activity relationships of the compounds were determined. Concerning erythrocytes, we analyzed the antioxidant activity of the compounds and their impact on the RBCs' shape and transmembrane potential. The compounds' cytotoxic activity, ability to modulate apoptosis, cell cycle, and intracellular ROS generation, as well as inhibitory activity against AAPH-inducted oxidative stress, were determined in relation to HMEC-1 cells. We demonstrated that biological activity of cyanidin and its

Indexed as

AnimalsAnthocyaninsApoptosisCell CycleCell LineCell ShapeCell SurvivalCytoprotectionEndothelial CellsErythrocytesGlycosylationHemolysisHumansMembrane PotentialsMicrovesselsOxidative StressAnthocyaninscyanidinReactive Oxygen SpeciesanthocyaninsapoptosisHMEC-1intracellular ROSRBCsSARstoxicity

Identifiers

PMID31010130
PMCPMC6514962
OpenAlexW2937622034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.