Evidence map›Paper›PMID 31010127›Full record

ArticleInternational journal of molecular sciences2019

Moringin from

Santa Cirmi, Nadia Ferlazzo, Agnese Gugliandolo, Laura Musumeci, Emanuela Mazzon, Alessia Bramanti, Michele Navarra

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
11.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 72 citations in OpenAlex.

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  14. International journal of molecular sciences · 2023
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  20. Mechanistic Wound Healing and Antioxidant Potential ofAntioxidants (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Santa CirmiDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, Italy. scirmi@unime.it.ORCID 0000-0002-6916-0307
Nadia FerlazzoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, Italy. nferlazzo@unime.it.
Agnese GugliandoloIRCCS Centro Neurolesi "Bonino-Pulejo", 98124 Messina, Italy. agnese.gugliandolo@irccsme.it.
Laura MusumeciDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, Italy. lauramusumeci93@gmail.com.
Emanuela MazzonIRCCS Centro Neurolesi "Bonino-Pulejo", 98124 Messina, Italy. emanuela.mazzon@irccsme.it.
Alessia BramantiIRCCS Centro Neurolesi "Bonino-Pulejo", 98124 Messina, Italy. alessia.bramanti@gmail.com.
Michele NavarraDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, Italy. mnavarra@unime.it.ORCID 0000-0002-6492-7820
University of Messina · ITCentro Neurolesi Bonino Pulejo · ITInstitute of Applied Science and Intelligent Systems · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decades, glucosinolates (GLs), precursors of isothiocyanates (ITCs), have been studied mostly for their chemopreventive and chemotherapeutic properties. The aim of our research was to study the antiproliferative effect of 4-(α-L-rhamnopyranosyloxy) benzyl glucosinolate (glucomoringin; GMG) bioactivated by myrosinase enzyme to form the corresponding isothiocyanate 4-(α-L-rhamnopyranosyloxy) benzyl C (moringin) in SH-SY5Y human neuroblastoma cells. We found that moringin significantly reduced SH-SY5Y cell growth in a time and concentration-dependent (

Indexed as

ApoptosisApoptosis Regulatory ProteinsCell Cycle CheckpointsCell Line, TumorCell ProliferationCell ShapeG2 PhaseGene Expression Regulation, NeoplasticHumansIsothiocyanatesMoringa oleiferaNeuroblastomaNF-kappa BSeedsApoptosis Regulatory ProteinsIsothiocyanatesmoringinNF-kappa BapoptosiscancerglucosinolatesisothiocyanateMoringa oleiferamoringinSH-SY5Y cells

Identifiers

PMID31010127
PMCPMC6515259
OpenAlexW2936589723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.