Evidence map›Paper›PMID 31010117›Full record

ArticleMolecules (Basel, Switzerland)2019

Propolis Induces AQP3 Expression: A Possible Way of Action in Wound Healing.

Simona Martinotti, Giorgia Pellavio, Umberto Laforenza, Elia Ranzato

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Propolis: A Natural Substance with Multifaceted Properties and Activities.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Understanding the Anticancer Properties of Honey.International journal of molecular sciences · 2024
    Review
  9. The effect of green synthesis of TiOVeterinary medicine and science · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Research Progress on Therapeutic Effect and Mechanism of Propolis on Wound Healing.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  17. "Green" Biomaterials: The Promising Role of Honey.Journal of functional biomaterials · 2021
    Review
  18. Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated HInternational journal of molecular sciences · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Simona MartinottiDiSIT-Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, 15121 Alessandria, Italy. simona.martinotti@uniupo.it.ORCID 0000-0003-2891-1810
Giorgia PellavioDepartment of Molecular Medicine, Human Physiology Unit, University of Pavia, 27100 Pavia, Italy. giorgia.pellavio01@universitadipavia.it.
Umberto LaforenzaDepartment of Molecular Medicine, Human Physiology Unit, University of Pavia, 27100 Pavia, Italy. lumberto@unipv.it.ORCID 0000-0003-2951-5983
Elia RanzatoDiSIT-Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Piazza Sant'Eusebio 5, 13100 Vercelli, Italy. elia.ranzato@uniupo.it.ORCID 0000-0002-7600-8215
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Pavia · IT

Funding

This work was granted by financial support (ER) of the University del Piemonte Orientale (Ricerca Locale 2015). ricerca locale 2015
6 · The paper itself

Abstract

Propolis is the generic name of a complex of resinous compound collected by honeybees and it has been utilized for many years in folk medicine. As other products generated by honeybees (such as royal jelly, pollen, honey), propolis has great therapeutic properties, but very little scientific information is available. Therefore, this study was aimed at exploring the potential wound healing properties of propolis. To that end, we utilized an in vitro scratch wound healing model consisting of human immortalized keratinocytes. Our scratch wound data clearly demonstrated that propolis induced a pronounced increase in the wound repair abilities of keratinocytes. A cell migration assay showed that propolis stimulated keratinocytes to close the wound. We revealed the role of H

Indexed as

Aquaporin 3Cell MembraneHumansHydrogen PeroxideKeratinocytesPropolisWound HealingAquaporin 3Hydrogen PeroxidePropolisaquaporin-3migrationpropolisROSwound repair

Identifiers

PMID31010117
PMCPMC6515181
OpenAlexW2937478373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.