Evidence map›Paper›PMID 31010019›Full record

ArticleMolecules (Basel, Switzerland)2019

Impact of Small Molecules on Intermolecular G-Quadruplex Formation.

Prabesh Gyawali, Keshav Gc, Yue Ma, Sanjaya Abeysirigunawardena, Kazuo Nagasawa, Hamza Balci

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Prabesh GyawaliDepartment of Physics, Kent State University, Kent, OH 44242, USA. pgyawal2@kent.edu.
Keshav GcDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA. kgc@kent.edu.
Yue MaDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan. yue-ma@m2.tuat.ac.jp.ORCID 0000-0002-0437-948X
Sanjaya AbeysirigunawardenaDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA. sabeysir@kent.edu.
Kazuo NagasawaDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan. knaga@cc.tuat.ac.jp.ORCID 0000-0002-0437-948X
Hamza BalciDepartment of Physics, Kent State University, Kent, OH 44242, USA. hbalci@kent.edu.
Kent State University · USTokyo University of Agriculture and Technology · JP

Funding

Influence of small molecules on G-quadruplex stability, folding kinetics, and interactions with proteinsR15GM123443 · NIGMS · KENT STATE UNIVERSITY · PI BALCI, HAMZA · 2018 to 2018
$438k
A Single Molecule Exploration of Protein and G-quadruplex InteractionsR15GM109386 · NIGMS · KENT STATE UNIVERSITY · PI BALCI, HAMZA · 2015 to 2015
$346k
NIGMS NIH HHS R15 GM109386NIGMS NIH HHS R15 GM123443NIH HHS 1R15GM109386NIH HHS 1R15GM123443
6 · The paper itself

Abstract

We performed single molecule studies to investigate the impact of several prominent small molecules (the oxazole telomestatin derivative L2H2-6OTD, pyridostatin, and Phen-DC

Indexed as

Drug DiscoveryG-QuadruplexesMolecular StructureNucleic Acid ConformationOxazolesTrinucleotide RepeatsOxazolesbiosensorFRETG-quadruplexsingle moleculesmall molecule

Identifiers

PMID31010019
PMCPMC6514588
OpenAlexW2940147131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.