Evidence map›Paper›PMID 31010013›Full record

ArticleViruses2019

Periplasmic Nanobody-APEX2 Fusions Enable Facile Visualization of Ebola, Marburg, and Mĕnglà virus Nucleoproteins, Alluding to Similar Antigenic Landscapes among

Laura J Sherwood, Andrew Hayhurst

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Conserved Filovirus Proteins as Targets of Broad-Spectrum Antivirals.bioRxiv : the preprint server for biology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laura J SherwoodDisease Intervention and Prevention, Texas Biomedical Research Institute, 8715 W. Military Dr., San Antonio, TX 78227-5302, USA. lsherwood@txbiomed.org.
Andrew HayhurstDisease Intervention and Prevention, Texas Biomedical Research Institute, 8715 W. Military Dr., San Antonio, TX 78227-5302, USA. ahayhurst@txbiomed.org.
Texas Biomedical Research Institute · US

Funding

Mechanism and Evolution of Filoviral Monoclonal Affinity Reagent Sandwich AssaysR01AI112851 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI HAYHURST, ANDREW · 2015 to 2019
$2.4M
National Institute of Allergy and Infectious Diseases R01AI112851
6 · The paper itself

Abstract

We explore evolved soybean ascorbate peroxidase (APEX2) as a reporter when fused to the C-termini of llama nanobodies (single-domain antibodies, sdAb; variable domains of heavy chain-only antibodies, VHH) targeted to the

Indexed as

AnimalsAscorbate PeroxidasesColorimetryEbolavirusEnzyme-Linked Immunosorbent AssayFiloviridaeHEK293 CellsHumansMarburgvirusModels, MolecularNucleoproteinsOptical ImagingPeriplasmSingle-Domain AntibodiesViral Fusion ProteinsAscorbate PeroxidasesNucleoproteinsSingle-Domain AntibodiesViral Fusion ProteinsAPEX2EbolaFilovirusMarburgnanobodynanoluciferasenucleoproteinperoxidasesdAbVHH

Identifiers

PMID31010013
PMCPMC6521291
OpenAlexW2937950658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.