Evidence map›Paper›PMID 31009990›Full record

ArticleNutrients2019

Feralgine™ a New Approach for Iron Deficiency Anemia in Celiac Patients.

Laura Giancotti, Valentina Talarico, Giuseppe Antonio Mazza, Santina Marrazzo, Pietro Gangemi, Roberto Miniero, Marco Bertini

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  6. [Effect of iron deficiency level on oral iron absorption].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2021
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Laura GiancottiDepartment of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy. lauragiancotti@virgilio.it.
Valentina TalaricoDepartment of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy. talaricovalentina@gmail.com.
Giuseppe Antonio MazzaDepartment of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy. giuseppeantiom@gmail.com.
Santina MarrazzoDepartment of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy. santina.marrazzo.ost@live.it.
Pietro GangemiClinical Chemistry Laboratory, Pugliese-Ciaccio Hospital, 88100 Catanzaro, Italy. piero19532@virgilio.it.
Roberto MinieroDepartment of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy. roberto.miniero@unicz.it.
Marco BertiniR&D Department, Laboratori Baldacci SpA, 56124 Pisa, Italy. bertini@baldaccilab.com.ORCID 0000-0003-1469-7825
Magna Graecia University · ITAzienda Ospedaliera Pugliese Ciaccio · ITBaldacci (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCeliac disease (CD) is an immunologically-mediated disorder characterized by duodenal mucosa villi atrophy. Iron absorption is usually reduced in celiac patients making every kind of oral iron treatment unhelpful because of malasorption. Feralgine™ is a new product that has been demonstrated to be more bioavailable. As such, the aim of our study was to evaluate the absorption of Feralgine™ in adult patients with CD.

methodsTwenty-six adults affected by Iron Deficiency Anemia (IDA), of which 14 were also affected by CD and 12 were not affected by CD, were enrolled. An oral iron absorption test (OIAT) was performed in each patient by administrating Feralgine™, and serum iron was evaluated at baseline (T0) and after 2 h (T1) from the oral iron ingestion.

resultsThe OIAT was well tolerated in all patients, and, surprisingly, an equivalent statistically significant improvement in serum iron occurred in the two groups of patients (IDA plus CD: T0 = 28.21 µg/dL vs. T1 = 94.14 µg/dL

conclusionsThese results demonstrated the high absorption of Feralgine™ in celiac patients, confirming our previous data obtained with Ferrous Bysglicinate in children with CD.

Indexed as

Intestinal AbsorptionIron DeficienciesAdministration, OralAdultAlginatesAnemia, Iron-DeficiencyBiological AvailabilityCeliac DiseaseFemaleFerrous CompoundsGlycineHumansIronMaleAlginatesferrous bisglycinateFerrous CompoundsGlycineIronceliac diseaseferrous bisglycinate chelate alginateiron deficiency anemiaoral iron absorption test

Identifiers

PMID31009990
PMCPMC6520849
OpenAlexW2940362511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.