← Diet, exercise & lifestyle × body weight & composition

TrialAnnals of internal medicine2019

Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study.

John W Apolzan et al.PubMed ↗Full text ↗Publisher ↗

It states no comparison between the randomised groups of NCT00004992. The report of the trial’s main result is not on the map, and the numbers here are shown and do not vote.

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… maintained between years 6 and 15 was 6.2% (95% CI, 5.2% to 7.2%) in the metformin group, 3.7% (CI, 3.1% to 4.4%) in the ILS group, and 2.8% (CI, 1.3% to 4.4%) in the …

← favours treatmentfavours comparator →
could be chance
Mean weight loss relative to baseline that was maintained between years 6 and 15metformin vs baseline weight, in participants who lost at least 5% of baseline weight in the first year
−6.20−7.20 to −5.20
Mean weight loss relative to baseline that was maintained between years 6 and 15intensive lifestyle intervention (ILS) vs baseline weight, in participants who lost at least 5% of baseline weight in the first year
−3.70−4.40 to −3.10
Mean weight loss relative to baseline that was maintained between years 6 and 15placebo vs baseline weight, in participants who lost at least 5% of baseline weight in the first year
−2.80−4.40 to −1.30
MetforminDiet, exercise & lifestyleBody weight & composition
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Full record →Abstract, authors, funding and every citing paper · PMID 31009939