Evidence map›Paper›PMID 31009822›Full record

ReviewCell calcium2019

CRAC channels and disease - From human CRAC channelopathies and animal models to novel drugs.

Stefan Feske

Open access · greenAbstract readReview
In one paragraph

Review in Cell calcium, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 96 citations in OpenAlex.

  1. Review
  2. Article
  3. Evolutionarily conserved hydrophobicity and sterics in TM3/TM4 balance Orai1 pore opening.Protein science : a publication of the Protein Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Multiple weak brakes act in concert to control STIM1 and store-operated calcium entry.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. STIM1 and lipid interactions at ER-PM contact sites.American journal of physiology. Cell physiology · 2025
    Review
  16. Article
  17. House dust mite allergens, store-operated CaThe Journal of physiology · 2024
    Review
  18. Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stefan FeskeDepartment of Pathology, New York University School of Medicine, New York, NY, 10016, USA. Electronic address: feskes01@nyumc.org.
New York University · US

Funding

CRAC Channel Deficiency in Immunity to InfectionR01AI097302 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2012 to 2022
$5.6M
Regulation of Follicular T cell Responses in the Lung by Ion ChannelsR01AI130143 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2017 to 2021
$2.4M
Regulation of encephalitogenic T cells by CRAC channelsR01AI137004 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2018 to 2022
$2.4M
Modulation of ORAI2 and ORAI3 Calcium ChannelsR21AI107448 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2016 to 2017
$466k
Identifying Novel Ion Channels Regulating T cell FunctionR21AI125997 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2016 to 2017
$466k
NIAID NIH HHS R01 AI097302NIAID NIH HHS R01 AI130143NIAID NIH HHS R01 AI137004NIAID NIH HHS R21 AI107448NIAID NIH HHS R21 AI125997
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsBlood Platelet DisordersCalciumCalcium Release Activated Calcium ChannelsCalcium SignalingChannelopathiesDisease Models, AnimalDrug DiscoveryDyslexiaErythrocytes, AbnormalHumansIchthyosisMigraine DisordersMiosisMuscle FatigueMutationCalciumCalcium Release Activated Calcium ChannelsNeoplasm ProteinsORAI1 ProteinSTIM1 protein, humanStromal Interaction Molecule 1CalciumCRAC channelDiseaseImmunodeficiencyMutationORAI1STIM1

Identifiers

PMID31009822
PMCPMC6545165
OpenAlexW2921398125

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.