ReviewFrontiers in neuroendocrinology2019
Experience-dependent mechanisms in the regulation of parental care.
Review in Frontiers in neuroendocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Neural circuits for mammalian parental behaviour.Nature reviews. Neuroscience · 2026Review
- Psilocybin during the postpartum period induces long-lasting adverse effects in both mothers and offspring.Nature communications · 2025Article
- Maternal singing and speech have beneficial effects on preterm infant's general movements at term equivalent age and at 3 months: an RCT.Frontiers in psychology · 2025Article
- Role of sexually dimorphic oxytocin receptor-expressing neurons in the anteroventral periventricular nucleus on maternal behavior.Peptides · 2024Review
- Roadmap for maternal behavior research in domestic dogs: lessons from decades of laboratory rodent work.Frontiers in veterinary science · 2024Review
- Psychostimulants and social behaviors.Frontiers in pharmacology · 2024Review
- Mother-Young Bonding: Neurobiological Aspects and Maternal Biochemical Signaling in Altricial Domesticated Mammals.Animals : an open access journal from MDPI · 2023Review
- An accessory prefrontal cortex-thalamus circuit sculpts maternal behavior in virgin female mice.The EMBO journal · 2022Article
- Optimization of Milk Substitutes for the Artificial Rearing of Chinese Tree Shrews (Animals : an open access journal from MDPI · 2022Article
- Effects of maternal experience on pup-induced activation of maternal neural circuits in virgin mice.Hormones and behavior · 2022Article
- Precise and Pervasive Phasic Bursting in Locus Coeruleus during Maternal Behavior in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Experience-Regulated Neuronal Signaling in Maternal Behavior.Frontiers in molecular neuroscience · 2022Review
- Alterations in corticotropin-releasing factor receptor type 1 in the preoptic area and hypothalamus in mice during the postpartum period.Hormones and behavior · 2021Article
- Neural Contributions of the Hypothalamus to Parental Behaviour.International journal of molecular sciences · 2021Review
- Flipping the parental switch: from killing to caring in male mammals.Animal behaviour · 2020Article
- Adaptations in reward-related behaviors and mesolimbic dopamine function during motherhood and the postpartum period.Frontiers in neuroendocrinology · 2020Review
- Review
- Environmental influences on placental programming and offspring outcomes following maternal immune activation.Brain, behavior, and immunity · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Maternal behavior is a defining characteristic of mammals, which is regulated by a core, conserved neural circuit. However, mothering behavior is not always a default response to infant conspecifics. For example, initial fearful, fragmented or aggressive responses toward infants in laboratory rats and mice can give way to highly motivated and organized caregiving behaviors following appropriate hormone exposure or repeated experience with infants. Therefore hormonal and/or experiential factors must be involved in determining the extent to which infants access central approach and avoidance neural systems. In this review we describe evidence supporting the idea that infant conspecifics are capable of activating distinct neural pathways to elicit avoidant, aggressive and parental responses from adult rodents. Additionally, we discuss the hypothesis that alterations in transcriptional regulation within the medial preoptic area of the hypothalamus may be a key mechanism of neural plasticity involved in programming the differential sensitivity of these neural pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.