Evidence map›Paper›PMID 31009470›Full record

Trial reportPloS one2019

Cost-effectiveness of acupuncture versus standard care for pelvic and low back pain in pregnancy: A randomized controlled trial.

Stephanie Nicolian, Thibault Butel, Laetitia Gambotti, Manon Durand, Antoine Filipovic-Pierucci, Alain Mallet, Mamadou Kone, Isabelle Durand-Zaleski, Marc Dommergues

Registry-linked trialAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01848587 (Trial of Acupuncture Pelvic and Low Back Pain in Pregnancy), which is not on this map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01848587 phase3completednot on this map

Trial of Acupuncture Pelvic and Low Back Pain in Pregnancy (TAPPP)

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2012 to 2015Enrolled200ConditionsDisorder of PregnancyArmsacupuncture, usual care
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stephanie NicolianAP-HP, Service de Gynécologie-Obstétrique- Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.ORCID 0000-0001-5597-189X
Thibault ButelAP-HP Unité de recherche clinique en économie de la santé-hôpital Hôtel-Dieu, Paris, France.
Laetitia GambottiAP-HP Unité de recherche Clinique, Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.
Manon DurandINSERM and AP-HP, CIC-1421, Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.
Antoine Filipovic-PierucciINSERM and AP-HP, CIC-1421, Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.
Alain MalletAP-HP Unité de recherche Clinique, Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.
Mamadou KoneAP-HP Unité de recherche Clinique, Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.
Isabelle Durand-ZaleskiAP-HP Unité de recherche clinique en économie de la santé-hôpital Hôtel-Dieu, Paris, France.
Marc DommerguesAP-HP, Service de Gynécologie-Obstétrique- Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.ORCID 0000-0001-9800-4525

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the cost-effectiveness of acupuncture for pelvic girdle and low back pain (PGLBP) during pregnancy.

designPragmatic-open-label randomised controlled trial.

settingFive maternity hospitals. POPULATION: Pregnant women with PGLBP.

method1:1 randomization to standard care or standard care plus acupuncture (5 sessions by an acupuncturist midwife).

main outcome measureEfficacy: proportion of days with self-assessed pain by numerical rating scale (NRS) ≤ 4/10. Cost effectiveness (societal viewpoint, time horizon: pregnancy): incremental cost per days with NRS ≤ 4/10. Indirect non-healthcare costs included daily compensations for sick leave and productivity loss caused by absenteeism or presenteeism.

results96 women were allocated to acupuncture and 103 to standard care (total 199). The proportion of days with NRS ≤ 4/10 was greater in the acupuncture group than in the standard care group (61% vs 48%, p = 0.007). The mean Oswestry disability score was lower in the acupuncture group than with standard care alone (33 versus 38, Δ = 5, 95% CI: 0.8 to 9, p = 0.02). Average total costs were higher in the control group (€2947) than in the acupuncture group (€2635, Δ = -€312, 95% CI: -966 to +325), resulting from the higher indirect costs of absenteeism and presenteeism. Acupuncture was a dominant strategy when both healthcare and non-healthcare costs were included. Costs for the health system (employer and out-of-pocket costs excluded) were slightly higher for acupuncture (€1512 versus €1452, Δ = €60, 95% CI: -272 to +470).

conclusionAcupuncture was a dominant strategy when accounting for employer costs. A 100% probability of cost-effectiveness was obtained for a willingness to pay of €100 per days with pain NRS ≤ 4.

Indexed as

Acupuncture TherapyAdolescentAdultCost-Benefit AnalysisExercise TherapyFemaleHumansLow Back PainPelvic PainPelvisPregnancyPregnancy ComplicationsQuality of LifeTreatment OutcomeYoung Adult

Identifiers

PMID31009470
PMCPMC6476478

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.