Evidence map›Paper›PMID 31009120›Full record

ArticleThe European journal of neuroscience2019

N-Methyl-d-aspartate receptor open-channel blockers memantine and magnesium modulate nociceptive trigeminovascular neurotransmission in rats.

Jan Hoffmann, Robin James Storer, Jeong-Wook Park, Peter J Goadsby

Open access · bronzeAbstract read
In one paragraph

Article in The European journal of neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Hemiplegic migraine: genetics and pathophysiology.The Journal of clinical investigation · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Glutamate as a Therapeutic Substrate in Migraine.International journal of molecular sciences · 2025
    Review
  7. Animal Models of Chronic Migraine: From the Bench to Therapy.Current pain and headache reports · 2024
    Review
  8. Review
  9. Spinal antinociceptive effect of the PnTx4(5-5) peptide is possibly mediated by the NMDA autoreceptors.The journal of venomous animals and toxins including tropical diseases · 2024
    Article
  10. Review
  11. The NMDA receptor antagonists memantine and ketamine as anti-migraine agents.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Review
  12. Review
  13. Article
  14. A systematic review of the efficacy of ketamine for craniofacial pain.Canadian journal of pain = Revue canadienne de la douleur · 2023
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 4 countries.

Jan HoffmannDepartment of Neurology, University of California, San Francisco, California, USA.ORCID 0000-0002-2103-9081
Robin James StorerDepartment of Neurology, University of California, San Francisco, California, USA.ORCID 0000-0003-0157-2919
Jeong-Wook ParkDepartment of Neurology, Catholic University, Seoul, South Korea.
Peter J GoadsbyDepartment of Neurology, University of California, San Francisco, California, USA.ORCID 0000-0003-3260-5904
University of California, San Francisco · USCatholic University of Korea · KRChulalongkorn University · TH

Funding

Wellcome Trust 104033
6 · The paper itself

Abstract

Experimental and clinical studies suggest that the low-affinity N-methyl-d-aspartate (NMDA) receptor open-channel blockers Mg

Indexed as

AnimalsExcitatory Amino Acid AntagonistsGlutamic AcidMagnesiumMaleMemantineNeuronsN-MethylaspartateNociceptionRatsRats, Sprague-DawleyReceptors, N-Methyl-D-AspartateSynapsesSynaptic TransmissionTrigeminal NucleiExcitatory Amino Acid AntagonistsGlutamic AcidMagnesiumMemantineN-MethylaspartateReceptors, N-Methyl-D-Aspartateglutamateheadachemicroiontophoresismigrainenaratriptan

Identifiers

PMID31009120
PMCPMC7611086
OpenAlexW2941895150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.