Evidence map›Paper›PMID 31009089›Full record

ArticleMicrobiology and immunology2019

Structures of a highly variable cell-wall anchored protein-encoding the spj gene from ST8/SCCmecIVl community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA/J) isolated from 2003 onwards: An indicator of a strongly invasive pathotype.

Tsai-Wen Wan, Lee-Jene Teng, Tatsuo Yamamoto

Open access · hybridAbstract read
In one paragraph

Article in Microbiology and immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Transposition of TnAntimicrobial agents and chemotherapy · 2025
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Tsai-Wen WanDepartment of Epidemiology, Genomics, and Evolution, International Medical Education and Research Center, Niigata, Japan.
Lee-Jene TengLaboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, Taiwan.
Tatsuo YamamotoDepartment of Epidemiology, Genomics, and Evolution, International Medical Education and Research Center, Niigata, Japan.
Taipei Medical University · TWEvolutionary Genomics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell wall-anchored protein-encoding spj gene on staphylococcal cassette chromosome mec IVl (SCCmecIVl) was found to vary in size because of its 22- and 86-aa repeat domains. The 22-aa repeats are the more flexible of the two repeats, comprising three 11-aa units, and were classified into three groups with eleven types. The 11/22-aa repeats are longer in individuals with bullous impetigo, shorter in those with invasive disease and were absent in a fatal case, this last one having been rapidly diagnosed by PCR. IS431-flanking pUB110 (bleO, aadD) is present on SCCmecIVl at 90%. The bacterial surface has the spj product and a unique surface layer.

Indexed as

Bacterial ProteinsCell WallCommunity-Acquired InfectionsHumansMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsVirulenceBacterial Proteinscell wall-anchored proteincommunity-associated methicillin-resistant Staphylococcus aureuspUB110staphylococcal cassette chromosome mec IVl

Identifiers

PMID31009089
PMCPMC6617794
OpenAlexW2941785151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.