Evidence map›Paper›PMID 31008842›Full record

ArticleSexually transmitted diseases2019

Serological Markers for Syphilis Among Persons Presenting With Syndromes Associated With Sexually Transmitted Infections: Results From the Zimbabwe STI Etiology Study.

Cornelis A Rietmeijer, More Mungati, Peter H Kilmarx, Beth Tippett Barr, Elizabeth Gonese, Ranmini S Kularatne, David A Lewis, Jeffrey D Klausner, Luanne Rodgers, H Hunter Handsfield

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Article in Sexually transmitted diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cornelis A RietmeijerFrom the Rietmeijer Consulting, LLC, Denver, CO.
More MungatiElizabeth Glazer Pediatric AIDS Foundation, Lesotho.
Peter H KilmarxFrom the Rietmeijer Consulting, LLC, Denver, CO.
Beth Tippett BarrCenters for Disease Control and Prevention, Division of Global Health and Tuberculosis, Harare, Zimbabwe.
Elizabeth GoneseCenters for Disease Control and Prevention, Division of Global Health and Tuberculosis, Harare, Zimbabwe.
Ranmini S KularatneCentre for HIV and STIs, National Institute for Communicable Diseases, Johannesburg, South Africa.
David A LewisWestern Sydney Sexual Health Centre, Parramatta, New South Wales, Australia.
Jeffrey D KlausnerDepartment of Medicine, Division of Infectious Diseases and Center for World Health, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA.
Luanne RodgersBiomedical Research and Training Institute, Harare, Zimbabwe.
H Hunter HandsfieldUniversity of Washington School of Medicine, Seattle, WA.

Funding

Intramural CDC HHS CC999999PEPFAR
6 · The paper itself

Abstract

backgroundSyphilis prevalence in sub-Saharan Africa appears to be stable or declining but is still the highest globally. Ongoing sentinel surveillance in high-risk populations is necessary to inform management and detect changes in syphilis trends. We assessed serological syphilis markers among persons with sexually transmitted infections in Zimbabwe.

methodsWe studied a predominantly urban, regionally diverse group of women and men presenting with genital ulcer disease (GUD), women with vaginal discharge and men with urethral discharge at clinics in Zimbabwe. Syphilis tests included rapid plasma reagin and the Treponema pallidum hemagglutination assay.

resultsAmong 436 evaluable study participants, 36 (8.3%) tested positive for both rapid plasma reagin and Treponema pallidum hemagglutination assay: women with GUD: 19.2%, men with GUD: 12.6%, women with vaginal discharge: 5.7% and men with urethral discharge: 1.5% (P < 0.0001).

conclusionsSyphilis rates in Zimbabwe are high in sentinel populations, especially men and women with GUD.

Indexed as

AdolescentAdultBiomarkersFemaleGenitaliaHumansMaleMiddle AgedPrevalenceSentinel SurveillanceSexually Transmitted DiseasesSyphilisTreponema pallidumUlcerUrban PopulationVaginal DischargeBiomarkers

Identifiers

PMID31008842
PMCPMC6885999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.