Evidence map›Paper›PMID 31008706›Full record

SynthesisJournal of medical Internet research2019

The Evidence Base for an Ideal Care Pathway for Frail Multimorbid Elderly: Combined Scoping and Systematic Intervention Review.

Gro Berntsen, Frode Strisland, Kristian Malm-Nicolaisen, Berglind Smaradottir, Rune Fensli, Mette Røhne

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05593835 (Protocol for a Cluster Randomised Trial of a Goal-Oriented Care Approach for Multimorbidity Patients Supported by a Digital Platform), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05593835 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Protocol for a Cluster Randomised Trial of a Goal-Oriented Care Approach for Multimorbidity Patients Supported by a Digital Platform

TypeinterventionalSponsorUniversidade Nova de LisboaRan2025 to 2027Enrolled1,380ConditionsChronic DiseaseArmsMETHIS Platform, Goal-Oriented Care Training Program
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. National and Subnational Models of Care That Support Primary Health Care: A Mixed-Methods Study.The International journal of health planning and management · 2026
    Article
  7. Article
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  9. Moving forward, leaving the patients behind? A multilevel assessment framework for evaluating patient-centred, integrated care quality.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Review
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  11. Article
  12. Review
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  17. A codesigned fit-for-purpose implementation framework for aged care.Journal of evaluation in clinical practice · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gro BerntsenNorwegian Center for E-health Research, University Hospital of North Norway, Tromsø, Norway.ORCID 0000-0002-3294-4263
Frode StrislandSINTEF Digital, Oslo, Norway.ORCID 0000-0003-4628-3280
Kristian Malm-NicolaisenNorwegian Center for E-health Research, University Hospital of North Norway, Tromsø, Norway.ORCID 0000-0001-9603-8342
Berglind SmaradottirCentre for eHealth, University of Agder, Grimstad, Norway.ORCID 0000-0002-4560-1227
Rune FensliCentre for eHealth, University of Agder, Grimstad, Norway.ORCID 0000-0003-3525-7677
Mette RøhneSINTEF Digital, Oslo, Norway.ORCID 0000-0002-2252-2542
SINTEF · NOUniversity Hospital of North Norway · NOUniversity of Agder · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a call for bold and innovative action to transform the current care systems to meet the needs of an increasing population of frail multimorbid elderly. International health organizations propose complex transformations toward digitally supported (1) Person-centered, (2) Integrated, and (3) Proactive care (Digi-PIP care). However, uncertainty regarding both the design and effects of such care transformations remain. Previous reviews have found favorable but unstable impacts of each key element, but the maturity and synergies of the combination of elements are unexplored.

objectiveThis study aimed to describe how the literature on whole system complex transformations directed at frail multimorbid elderly reflects (1) operationalization of intervention, (2) maturity, (3) evaluation methodology, and (4) effect on outcomes.

methodsWe performed a systematic health service and electronic health literature review of care transformations targeting frail multimorbid elderly. Papers including (1) Person-centered, integrated, and proactive (PIP) care; (2) at least 1 digital support element; and (3) an effect evaluation of patient health and/ or cost outcomes were eligible. We used a previously published ideal for the quality of care to structure descriptions of each intervention. In a secondary deductive-inductive analysis, we collated the descriptions to create an outline of the generic elements of a Digi-PIP care model. The authors then reviewed each intervention regarding the presence of critical elements, study design quality, and intervention effects.

resultsOut of 927 potentially eligible papers, 10 papers fulfilled the inclusion criteria. All interventions idealized Person-centered care, but only one intervention made what mattered to the person visible in the care plan. Care coordinators responsible for a whole-person care plan, shared electronically in some instances, was the primary integrated care strategy. Digitally supported risk stratification and management were the main proactive strategies. No intervention included workflow optimization, monitoring of care delivery, or patient-reported outcomes. All interventions had gaps in the chain of care that threatened desired outcomes. After evaluation of study quality, 4 studies remained. They included outcome analyses on patient satisfaction, quality of life, function, disease process quality, health care utilization, mortality, and staff burnout. Only 2 of 24 analyses showed significant effects.

conclusionsDespite a strong common-sense belief that the Digi-PIP ingredients are key to sustainable care in the face of the silver tsunami, research has failed to produce evidence for this. We found that interventions reflect a reductionist paradigm, which forces care workers into standardized narrowly focused interventions for complex problems. There is a paucity of studies that meet complex needs with digitally supported flexible and adaptive teamwork. We predict that consistent results from care transformations for frail multimorbid elderly hinges on an individual care pathway, which reflects a synergetic PIP approach enabled by digital support.

Indexed as

AgedFrail ElderlyHumansPatient SatisfactionQualitative ResearchQuality of Health Caredelivery of health care, integratedpatient-centered carerisk managementsecondary preventionsystematic review

Identifiers

PMID31008706
PMCPMC6658285
OpenAlexW2912823506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.